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complement activation

Term Information

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Accession
GO:0006956
Name
complement activation
Ontology
biological_process
Synonyms
complement cascade, complement response, complement activity
Alternate IDs
None
Definition
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Source: ISBN:0781735149, GOC:add, GO_REF:0000022
Comment
None
History
See term history for GO:0006956 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of complement activation (GO:0006956)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
complement activation [BFO:0000051 relation] BFO:0000051  protein activation cascade (GO:0072376)
complement activation [is_a relation] is_a  activation of immune response (GO:0002253)
complement activation [is_a relation] is_a  immune effector process (GO:0002252)
complement activation [is_a relation] is_a  humoral immune response (GO:0006959)
Children of complement activation (GO:0006956)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
activation of membrane attack complex (GO:0001905) [is_a relation] is_a  complement activation
complement-dependent cytotoxicity (GO:0097278) [BFO:0000051 relation] BFO:0000051  complement activation
regulation of complement activation (GO:0030449) [RO:0002211 relation] RO:0002211  complement activation
negative regulation of complement activation (GO:0045916) [RO:0002212 relation] RO:0002212  complement activation
complement activation, alternative pathway (GO:0006957) [is_a relation] is_a  complement activation
positive regulation of complement activation (GO:0045917) [RO:0002213 relation] RO:0002213  complement activation
complement activation, classical pathway (GO:0006958) [is_a relation] is_a  complement activation
complement activation, lectin pathway (GO:0001867) [is_a relation] is_a  complement activation
None.