AmiGO 2: Term Details for "mitotic checkpoint complex" (GO:0033597)

Accession: GO:0033597
Name: mitotic checkpoint complex
Ontology: cellular_component
Synonyms: MCC
Alternate IDs: None
Definition: A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20. Source: PMID:11726501, PMID:17650307, PMID:10704439, PMID:11535616
Comment: None
History: See term history for GO:0033597 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to mitotic checkpoint complex (excluding "regulates").; Link to all direct and indirect annotations to mitotic checkpoint complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for mitotic checkpoint complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
mitotic checkpoint complex	is_a	nuclear protein-containing complex (GO:0140513)
mitotic checkpoint complex	BFO:0000051	bub1-bub3 complex (GO:1990298)

subject	relation	object
mitotic checkpoint complex assembly (GO:1905660)	RO:0002588	mitotic checkpoint complex
mitotic checkpoint complex, CDC20-MAD2 subcomplex (GO:1990333)	BFO:0000050	mitotic checkpoint complex

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