AmiGO 2: Term Details for "indoleamine 2,3-dioxygenase activity" (GO:0033754)

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Term Information

Accession: GO:0033754
Name: indoleamine 2,3-dioxygenase activity
Ontology: molecular_function
Synonyms: IDO, D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity, tryptophan pyrrolase activity
Alternate IDs: None
Definition: Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine. Source: EC:1.13.11.52
Comment: None
History: See term history for GO:0033754 at QuickGO
Chem. react.: has participant N-formyl-D-kynurenine zwitterion; has participant D-tryptophan zwitterion; has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to indoleamine 2,3-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to indoleamine 2,3-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for indoleamine 2,3-dioxygenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0051213 dioxygenase activity
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0033754 indoleamine 2,3-dioxygenase activity

Parents of indoleamine 2,3-dioxygenase activity (GO:0033754)

subject	relation	object
indoleamine 2,3-dioxygenase activity	RO:0000057	N-formyl-D-kynurenine zwitterion (CHEBI:60051)
indoleamine 2,3-dioxygenase activity	is_a	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702)
indoleamine 2,3-dioxygenase activity	RO:0000057	D-tryptophan zwitterion (CHEBI:57719)
indoleamine 2,3-dioxygenase activity	RO:0000057	dioxygen (CHEBI:15379)

This term has no children.

EC: 1.13.11.52
MetaCyc: RXN-8664; RXN-8665
RHEA: 14189