AmiGO 2: Term Details for "homoisocitrate dehydrogenase activity" (GO:0047046)

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Term Information

Accession: GO:0047046
Name: homoisocitrate dehydrogenase activity
Ontology: molecular_function
Synonyms: 3-carboxy-2-hydroxyadipate dehydrogenase activity, (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity, (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating), (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating), 2-hydroxy-3-carboxyadipate dehydrogenase activity, 3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity, 3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating), homoisocitric dehydrogenase activity
Alternate IDs: GO:0047984
Definition: Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate. Source: EC:1.1.1.87
Comment: Note that EC:1.1.1.155 was merged into EC:1.1.1.87 as they are identical.
History: See term history for GO:0047046 at QuickGO
Chem. react.: has participant NADH(2-); has participant carbon dioxide; has participant 2-oxoadipate(2-); has participant (-)-homoisocitrate(3-); has participant NAD(1-)
Subset: None
Related: Link to all genes and gene products annotated to homoisocitrate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to homoisocitrate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for homoisocitrate dehydrogenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047046 homoisocitrate dehydrogenase activity

Parents of homoisocitrate dehydrogenase activity (GO:0047046)

subject	relation	object
homoisocitrate dehydrogenase activity	RO:0000057	NADH(2-) (CHEBI:57945)
homoisocitrate dehydrogenase activity	RO:0000057	carbon dioxide (CHEBI:16526)
homoisocitrate dehydrogenase activity	RO:0000057	2-oxoadipate(2-) (CHEBI:57499)
homoisocitrate dehydrogenase activity	RO:0000057	(-)-homoisocitrate(3-) (CHEBI:15404)
homoisocitrate dehydrogenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
homoisocitrate dehydrogenase activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

This term has no children.

EC: 1.1.1.87
MetaCyc: RXN-7970
RHEA: 11900