AmiGO 2: Term Details for "hyaluronan synthase activity" (GO:0050501)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0050501
Name: hyaluronan synthase activity
Ontology: molecular_function
Synonyms: alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity, alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity, seHAS, spHAS, HAS activity
Alternate IDs: None
Definition: Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP. Source: EC:2.4.1.212, MetaCyc:2.4.1.212-RXN
Comment: None
History: See term history for GO:0050501 at QuickGO
Chem. react.: has participant UDP(3-); has participant UDP-alpha-D-glucuronate(3-); has participant hyaluronate; has participant N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronate]; has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to hyaluronan synthase activity (excluding "regulates").; Link to all direct and indirect annotations to hyaluronan synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for hyaluronan synthase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0008194 UDP-glycosyltransferase activity
GO:0050501 hyaluronan synthase activity

Parents of hyaluronan synthase activity (GO:0050501)

subject	relation	object
hyaluronan synthase activity	RO:0000057	UDP(3-) (CHEBI:58223)
hyaluronan synthase activity	RO:0000057	UDP-alpha-D-glucuronate(3-) (CHEBI:58052)
hyaluronan synthase activity	RO:0000057	hyaluronate (CHEBI:132153)
hyaluronan synthase activity	RO:0000057	N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronate] (CHEBI:132154)
hyaluronan synthase activity	is_a	hexosyltransferase activity (GO:0016758)
hyaluronan synthase activity	RO:0000057	hydron (CHEBI:15378)
hyaluronan synthase activity	is_a	UDP-glycosyltransferase activity (GO:0008194)

This term has no children.

EC: 2.4.1.212
MetaCyc: 2.4.1.212-RXN
Reactome: R-HSA-2160851
RHEA: 12528