AmiGO 2: Term Details for "mitochondrial outer membrane permeabilization" (GO:0097345)

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Term Information

Accession: GO:0097345
Name: mitochondrial outer membrane permeabilization
Ontology: biological_process
Synonyms: MOMP, mitochondrion outer membrane permeabilization, mitochondrial outer membrane permeabilization during apoptotic cell death
Alternate IDs: None
Definition: The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. Source: GOC:BHF, PMID:21041309, GOC:mtg_apoptosis, GOC:pg
Comment: BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).
History: See term history for GO:0097345 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to mitochondrial outer membrane permeabilization (excluding "regulates").; Link to all direct and indirect annotations to mitochondrial outer membrane permeabilization (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for mitochondrial outer membrane permeabilization (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
UBERON:0000061 anatomical structure
GO:0110165 cellular anatomical entity
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0008150 biological_process
CL:0000000 cell
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0071840 cellular component organization or biogenesis
GO:0043229 intracellular organelle
GO:0051179 localization
GO:0043227 membrane-bounded organelle
GO:0065007 biological regulation
GO:0016043 cellular component organization
GO:0005737 cytoplasm
GO:0051234 establishment of localization
GO:0043231 intracellular membrane-bounded organelle
GO:0061024 membrane organization
GO:0005739 mitochondrion
GO:0007005 mitochondrion organization
GO:0006996 organelle organization
GO:0065008 regulation of biological quality
GO:0090559 regulation of membrane permeability
GO:0006810 transport
GO:0006915 apoptotic process
GO:0008219 cell death
GO:0007006 mitochondrial membrane organization
GO:0006839 mitochondrial transport
GO:1905710 positive regulation of membrane permeability
GO:0050789 regulation of biological process
GO:0046902 regulation of mitochondrial membrane permeability
GO:0050896 response to stimulus
GO:0008637 apoptotic mitochondrial changes
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0035794 positive regulation of mitochondrial membrane permeability
GO:0012501 programmed cell death
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death
GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:0097345 mitochondrial outer membrane permeabilization
GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Parents of mitochondrial outer membrane permeabilization (GO:0097345)

subject	relation	object
mitochondrial outer membrane permeabilization	BFO:0000050	apoptotic signaling pathway (GO:0097190)
mitochondrial outer membrane permeabilization	is_a	positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110)

Children of mitochondrial outer membrane permeabilization (GO:0097345)

subject	relation	object
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901030)	RO:0002213	mitochondrial outer membrane permeabilization
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901028)	RO:0002211	mitochondrial outer membrane permeabilization
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901029)	RO:0002212	mitochondrial outer membrane permeabilization

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