| Entry |
|
|---|
| Name |
5-FU;
Fluorouracil;
5-Fluorouracil
|
|---|
| Formula |
C4H3FN2O2
|
|---|
| Exact mass |
130.0179
|
|---|
| Mol weight |
130.08
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Reaction |
|
|---|
| Pathway |
| map00983 | Drug metabolism - other enzymes |
|
|---|
| Enzyme |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01B ANTIMETABOLITES
L01BC Pyrimidine analogues
L01BC02 Fluorouracil
D00584 Fluorouracil (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Antimetabolites
Fluorouracil
D00584 Fluorouracil (JP18/USP/INN)
Dermatological Agents
Dermatological Agents, Other
Warts and Actinic Keratosis Agents
Fluorouracil
D00584 Fluorouracil (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
422 Antimetabolites
4223 Fluorouracils
D00584 Fluorouracil (JP18/USP/INN)
Drug groups [BR:br08330]
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
DG01935 Fluoropyrimidine antineoplastic
DG00687 Fluorouracil
D00584 Fluorouracil
Metabolizing enzyme substrate
DG02984 DPYD substrate
DG00687 Fluorouracil
D00584 Fluorouracil
Drug classes [BR:br08332]
Antineoplastic
DG02018 Antimetabolite
D00584 Fluorouracil
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Methyltransferases
TYMS
D00584 Fluorouracil (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00584 Fluorouracil
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00584
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00584
Prodrugs [br08324.html]
D00584
Prodrugs [br08324.html]
C07649
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 9
1 C8y C 20.7957 -18.3013
2 C8y C 19.5791 -19.0057
3 N4x N 22.0068 -19.0057
4 O5x O 20.7843 -16.8981
5 C8x C 19.5791 -20.4030
6 X F 18.3622 -18.3013
7 C8y C 22.0068 -20.4030
8 N4x N 20.7957 -21.1017
9 O5x O 23.2061 -21.1017
BOND 9
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 5 8 1
8 7 9 2
9 7 8 1
|
|---|
