Entry Name Paclitaxel (JAN/USP/INN);
Product Generic PACLITAXEL (Alembic Pharmaceuticals Limited) ,
PACLITAXEL (Alembic Pharmaceuticals) ,
PACLITAXEL (BluePoint Laboratories) ,
PACLITAXEL (Fresenius Kabi USA) ,
PACLITAXEL (Gland Pharma Limited) ,
PACLITAXEL (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals) ,
PACLITAXEL (Hospira) ,
PACLITAXEL (MSN LABORATORIES PRIVATE LIMITED) ,
PACLITAXEL (Northstar Rx LLC) ,
PACLITAXEL (Novadoz Pharmaceuticals LLC) ,
PACLITAXEL (Sagent Pharmaceuticals) ,
PACLITAXEL (Sandoz) ,
PACLITAXEL (Teva Parenteral Medicines) ,
PACLITAXEL (Teva Parenteral Medicines) ,
PACLITAXEL PROTEIN-BOUND PARTICLES FOR INJECTABLE SUSPENSION (ALBUMIN-BOUND) (Apotex Corp.) ,
PACLITAXEL PROTEIN-BOUND PARTICLES FOR INJECTABLE SUSPENSION (ALBUMIN-BOUND) (Upsher-Smith Laboratories) Formula C47H51NO14
Exact mass 853.3310
Mol weight 853.90
Structure Mol file KCF file DB search Simcomp Neighbor Source Taxus brevifolia [TAX:
46220 ]
Class Metabolizing enzyme substrateDG02918 CYP2C8 substrateDG01633 CYP3A/CYP3A4 substrateDG02913 CYP3A4 substrate Remark Therapeutic category: 4240
Product (DG01430): D00491<JP /US>
Efficacy Antineoplastic, Tubulin depolymerization inhibitor
Disease Breast cancer [DS:
H00031 ]
Non-small cell lung cancer [DS:
H00014 ]
Adenocarcinoma of the pancreas [DS:
H00019 ]
Carcinoma of the ovary [DS:
H00027 ]
AIDS-related Kaposi's sarcoma [DS:
H00041 ]
Comment Taxane derivative
Target Pathway Metabolism Enzyme: CYP2C8 [HSA:
1558 ], CYP3A4 [HSA:
1576 ]
Interaction DDI search
Structure map map07042 Antineoplastics - agents from natural products
Other map Brite Anatomical Therapeutic Chemical (ATC) classification [BR:br08303 ]br08302 ]br08301 ]br08330 ]br08310 ]br08329.html ]br08309.html ]br08330 ] BRITE hierarchy Other DBs LinkDB All DBs KCF data Show
