KEGG   PATHWAY: ko00430
Entry
ko00430                     Pathway                                
Name
Taurine and hypotaurine metabolism
Class
Metabolism; Metabolism of other amino acids
Pathway map
ko00430  Taurine and hypotaurine metabolism
ko00430

Module
M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ko00430]
Other DBs
GO: 0019530
Orthology
K00456  cysteine dioxygenase [EC:1.13.11.20]
K01580  glutamate decarboxylase [EC:4.1.1.15]
K18966  sulfinoalanine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.29 4.1.1.11]
K10712  cysteamine dioxygenase [EC:1.13.11.19]
K00485  dimethylaniline monooxygenase (N-oxide forming) / hypotaurine monooxygenase [EC:1.14.13.8 1.8.1.-]
K00681  gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K18592  gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00659  bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K03119  taurine dioxygenase [EC:1.14.11.17]
K03851  taurine-pyruvate aminotransferase [EC:2.6.1.77]
K00259  alanine dehydrogenase [EC:1.4.1.1]
K19244  alanine dehydrogenase [EC:1.4.1.1]
K15372  taurine---2-oxoglutarate transaminase [EC:2.6.1.55]
K15371  glutamate dehydrogenase [EC:1.4.1.2]
K00260  glutamate dehydrogenase [EC:1.4.1.2]
K07255  taurine dehydrogenase small subunit [EC:1.4.2.-]
K07256  taurine dehydrogenase large subunit [EC:1.4.2.-]
K03852  sulfoacetaldehyde acetyltransferase [EC:2.3.3.15]
K00625  phosphate acetyltransferase [EC:2.3.1.8]
K13788  phosphate acetyltransferase [EC:2.3.1.8]
K15024  putative phosphotransacetylase [EC:2.3.1.8]
K00925  acetate kinase [EC:2.7.2.1]
K15373  sulfoacetaldehyde reductase [EC:1.1.1.313]
K25985  sulfoacetaldehyde reductase (NADH) [EC:1.1.1.433]
K19699  sulfoacetaldehyde dehydrogenase [EC:1.2.1.73]
K26005  sulfoacetate-CoA ligase [EC:6.2.1.-]
K15515  sulfoacetaldehyde dehydrogenase [EC:1.2.1.81]
K25261  isethionate sulfite-lyase [EC:4.4.1.38]
K25262  isethionate sulfite-lyase activating enzyme
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00033  Acetate
C00041  L-Alanine
C00084  Acetaldehyde
C00094  Sulfite
C00097  L-Cysteine
C00227  Acetyl phosphate
C00245  Taurine
C00506  L-Cysteate
C00519  Hypotaurine
C00593  Sulfoacetaldehyde
C00606  3-Sulfino-L-alanine
C01678  Cysteamine
C01959  Taurocyamine
C03149  N-Phosphotaurocyamine
C05122  Taurocholate
C05123  2-Hydroxyethanesulfonate
C05844  5-L-Glutamyl-taurine
C06735  Aminoacetaldehyde
C14179  Sulfoacetate
C19685  Sulfoacetyl-CoA
Reference
  Authors
Cook AM, Denger K.
  Title
Dissimilation of the C2 sulfonates.
  Journal
Arch Microbiol 179:1-6 (2002)
DOI:10.1007/s00203-002-0497-0
Reference
  Authors
Laue H, Cook AM.
  Title
Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia.
  Journal
Eur J Biochem 267:6841-8 (2000)
DOI:10.1046/j.1432-1033.2000.01782.x
Reference
  Authors
Ruff J, Denger K, Cook AM.
  Title
Sulphoacetaldehyde acetyltransferase yields acetyl phosphate: purification from Alcaligenes defragrans and gene clusters in taurine degradation.
  Journal
Biochem J 369:275-85 (2003)
DOI:10.1042/BJ20021455
Reference
  Authors
Bruggemann C, Denger K, Cook AM, Ruff J.
  Title
Enzymes and genes of taurine and isethionate dissimilation in Paracoccus denitrificans.
  Journal
Microbiology 150:805-16 (2004)
DOI:10.1099/mic.0.26795-0
Reference
  Authors
Denger K, Weinitschke S, Hollemeyer K, Cook AM.
  Title
Sulfoacetate generated by Rhodopseudomonas palustris from taurine.
  Journal
Arch Microbiol 182:254-8 (2004)
DOI:10.1007/s00203-004-0678-0
Reference
  Authors
Denger K, Ruff J, Schleheck D, Cook AM.
  Title
Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source.
  Journal
Microbiology 150:1859-67 (2004)
DOI:10.1099/mic.0.27077-0
Reference
  Authors
Styp von Rekowski K, Denger K, Cook AM.
  Title
Isethionate as a product from taurine during nitrogen-limited growth of Klebsiella oxytoca TauN1.
  Journal
Arch Microbiol 183:325-30 (2005)
DOI:10.1007/s00203-005-0776-7
Reference
PMID:4297098
  Authors
Jacobsen JG, Smith LH
  Title
Biochemistry and physiology of taurine and taurine derivatives.
  Journal
Physiol Rev 48:424-511 (1968)
DOI:10.1152/physrev.1968.48.2.424
Related
pathway
ko00270  Cysteine and methionine metabolism
ko00460  Cyanoamino acid metabolism
ko00480  Glutathione metabolism
ko00620  Pyruvate metabolism
ko00920  Sulfur metabolism
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