Entry Name Glycerophospholipid metabolism
Class Metabolism; Lipid metabolism
Pathway map rn00564 Glycerophospholipid metabolism
Ortholog table Module M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:rn00564 ]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:rn00564 ]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:rn00564 ]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:rn00564 ]
Other DBs Reaction R00748 ethanolamine-phosphate phosphate-lyase (deaminating; acetaldehyde-forming)
R00749 ethanolamine ammonia-lyase (acetaldehyde-forming)
R00842 sn-glycerol-3-phosphate:NAD+ 2-oxidoreductase
R00844 sn-glycerol-3-phosphate:NADP+ 2-oxidoreductase
R00846 sn-glycerol-3-phosphate:oxygen 2-oxidoreductase
R00848 sn-glycerol-3-phosphate:(acceptor) 2-oxidoreductase
R00851 acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
R00855 CDPglycerol phosphoglycerohydrolase
R00856 CTP:sn-glycerol-3-phosphate cytidylyltransferase
R01013 acyl-CoA:glycerone-phosphate O-acyltransferase
R01021 ATP:choline phosphotransferase
R01023 acetyl-CoA:choline O-acetyltransferase
R01026 acetylcholine aectylhydrolase
R01030 sn-glycero-3-phosphocholine glycerophosphohydrolase
R01310 phosphatidylcholine phosphatidohydrolase
R01312 phosphatidylcholine cholinephosphohydrolase
R01315 phosphatidylcholine 2-acylhydrolase
R01316 phosphatidylcholine 1-acylhydrolase
R01318 acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
R01319 acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase
R01320 S-adenosyl-L-methionine:phosphatidyl-N-dimethylethanolamine N-methyltransferase
R01321 CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase
R01468 ATP:ethanolamine O-phosphotransferase
R01470 sn-glycero-3-phosphoethanolamine glycerophosphohydrolase
R01797 CDP-diacylglycerol phosphatidylhydrolase
R01799 CTP:phosphatidate cytidyltransferase
R01800 CDP-diacylglycerol:L-serine 3-phosphatidyltransferase
R01801 CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase
R01802 CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
R01890 CTP:choline-phosphate cytidylyltransferase
R02027 phosphatidylglycerol cholinephosphohydrolase
R02029 phosphatidylglycerophosphate phosphohydrolase
R02030 CDP-diacylglycerol:phosphatidylglycerol 3-phosphatidyltransferase
R02037 S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase
R02038 CTP:ethanolamine-phosphate cytidylyltransferase
R02051 phosphatidylethanolamine phosphatidohydrolase
R02052 phosphatidylethanolamine ethanolaminephosphohydrolase
R02053 phosphatidylethanolamine 2-acylhydrolase
R02054 phosphatidylethanolamine 1-acylhydrolase
R02055 phsophatidyl-L-serine carboxy-lyase
R02056 S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase
R02057 CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
R02114 phosphatidylcholine:sterol O-acyltransferase
R02239 1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase
R02240 ATP:1,2-diacylglycerol 3-phosphotransferase
R02241 acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
R02242 acyl-CoA:2-acyl-sn-glycerol-3-phosphate O-acyltransferase
R02563 CDPethanolamine:L-serine ethanolaminephosphotransferase
R02746 1-acyl-sn-glycero-3-phosphocholine acylhydrolase
R02747 2-acyl-sn-glycero-3-phosphocholine acylhydrolase
R02817 serine-phosphoethanolamine ethanolaminephosphohydrolase
R03360 1-phosphatidyl-D-myo-inositol 2-acylhydrolase
R03416 1-acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase
R03417 L-2-lysophosphatidylethanolamine aldehydohydrolase
R03424 S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase
R04034 3-sn-phosphatidyl-L-serine sn-1 acylhydrolase
R04158 geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase
R04480 acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
R04520 geranylgeranyl-diphosphate:3-(O-geranylgeranyl)-sn-glycerol 1-phosphate geranylgeranyltransferase
R04864 2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
R05381 diethanolamine ethanolamine-lyase (acetaldehyde-forming)
R05382 triethanolamine diethanolamine-lyase (acetaldehyde-forming)
R05679 sn-glycerol-1-phosphate:NAD 2-oxidoreductase
R05680 sn-glycerol-1-phosphate:NADP 2-oxidoreductase
R05794 CDP-diacylglycerol:choline O-phosphatidyltransferase
R06868 S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase
R06869 S-adenosyl-L-methionine:phosphodimethylethanolamine N-methyltransferase
R06870 phosphoethanolamine phosphohydrolase
R06871 phosphocholine phosphohydrolase
R06872 acyl-CoA:sn-glycerol-3-phosphate 2-O-acyltransferase
R07376 L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
R08966 CTP:2,3-bis-(O-geranylgeranyl)-sn-glycerol-1-phosphate cytidylyltransferase
R09034 acyl-CoA:1-acyl-sn-glycero-3-phosphoinositol O-acyltransferase
R09035 acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase
R09036 acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase
R09038 cardiolipin acylhydrolase
R09072 S-adenosyl-L-methionine:1,2-diacyl-sn-glycerol 3-amino-3-carboxypropyltransferase
R09073 S-adenosylmethionine:diacylglycerylhomoserine N-methyltransferase (diacylglyceryl-N,N,N-trimethylhomoserine-forming)
R09944 CTP:1,2-diacyl-sn-glycerol 3-phosphotransferase
R10255 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol:L-serine 2,3-bis-(O-geranylgeranyl)-sn-glycerol phosphotransferase
R10325 2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NAD+ oxidoreductase
R10326 2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NADP+ oxidoreductase
R10331 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid:ferredoxin oxidoreductase
R11062 phosphatidylethanolamine:phosphatidylglycerol 3-phosphatidyltransferase
R12241 acyl phosphoate:sn-glycerol 3-phosphate acyltransferase
Compound C00093 sn-Glycerol 3-phosphate
C00350 Phosphatidylethanolamine
C00623 sn-Glycerol 1-phosphate
C00670 sn-Glycero-3-phosphocholine
C00681 1-Acyl-sn-glycerol 3-phosphate
C01194 1-Phosphatidyl-D-myo-inositol
C01210 N-Methylethanolamine phosphate
C01233 sn-Glycero-3-phosphoethanolamine
C01241 Phosphatidyl-N-methylethanolamine
C03372 Acylglycerone phosphate
C03819 1-Acylglycerophosphoinositol
C03872 L-Serine-phosphoethanolamine
C03892 Phosphatidylglycerophosphate
C03974 2-Acyl-sn-glycerol 3-phosphate
C04230 1-Acyl-sn-glycero-3-phosphocholine
C04233 2-Acyl-sn-glycero-3-phosphocholine
C04308 Phosphatidyl-N-dimethylethanolamine
C04438 1-Acyl-sn-glycero-3-phosphoethanolamine
C04590 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973 2-Acyl-sn-glycero-3-phosphoethanolamine
C05974 2-Acyl-sn-glycero-3-phosphoserine
C05976 Aminoacyl-phosphatidylglycerol
C13482 Phosphodimethylethanolamine
C18059 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125 1-Acyl-sn-glycero-3-phosphoserine
C18126 1-Acyl-sn-glycero-3-phosphoglycerol
C18168 Diacylglycerylhomoserine
C18169 Diacylglyceryl-N,N,N-trimethylhomoserine
C20466 2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518 2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340 Heptaprenylglyceryl phosphate
C22342 Diacetylheptaprenylglycerol
Reference Authors Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
Title The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
Journal Reference Authors Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
Title Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
Journal Reference Authors Athenstaedt K, Daum G.
Title Phosphatidic acid, a key intermediate in lipid metabolism.
Journal Reference Authors Shields DJ, Lehner R, Agellon LB, Vance DE.
Title Membrane topography of human phosphatidylethanolamine N-methyltransferase.
Journal Reference Authors Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
Title Pathways for phosphatidylcholine biosynthesis in bacteria.
Journal Reference Authors Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
Title Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
Journal Reference Authors Hsu L, Jackowski S, Rock CO
Title Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
Journal J Biol Chem 266:13783-8 (1991)
Reference Authors Stone SJ, Vance JE.
Title Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
Journal Related rn00010 Glycolysis / Gluconeogenesis
rn00260 Glycine, serine and threonine metabolism
rn00562 Inositol phosphate metabolism
rn00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
KO pathway LinkDB All DBs
