Entry Name Sphingolipid metabolism
Class Metabolism; Lipid metabolism
Pathway map Ortholog table Module M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:rn00600 ]
Other DBs Reaction R01281 palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)
R01494 N-acylsphingosine amidohydrolase
R01495 ATP:ceramide 1-phosphotransferase
R01496 acyl-CoA:sphingosine N-acyltransferase
R01497 UDP-glucose:N-acylsphingosine D-glucosyltransferase
R01498 D-glucosyl-N-acylsphingosine glucohydrolase
R01500 UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase
R01503 CDP-ethanolamine:ceramide phosphoethanolaminyltransferase
R01891 CDP-choline:N-acylsphingosine cholinephosphotransferase
R01926 ATP:sphingosine 1-phosphotransferase
R01928 UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
R01929 CDP-choline:sphingosine cholinephosphotransferase
R02464 sphinganine-1-phosphate pamlmitaldehyde-lyase
R02541 sphingomyelin cholinephosphohydrolase
R02542 sphingomyelin ceramide-phosphohydrolase
R02543 acyl-CoA:sphingosine N-acyltransferase
R02976 ATP:sphinganine 1-phosphotransferase
R02978 sphinganine:NADP+ 3-oxidoreductase
R03354 UDP-alpha-D-galactose:beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase
R03355 beta-D-galactosyl-1,4-beta-D-glucosylceramide galactohydrolase
R03492 GalNAc-beta1->4Gal-beta1->4Glc-beta1->1'Cer (GA2) N-acetylhexosaminohydrolase
R03617 D-galactosyl-N-acylsphingosine galactohydrolase
R03618 globotriosylceramide galactohydrolase
R04017 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase
R04018 acylneuraminyl hydrolase
R04019 digalactosylceramide galactohydrolase
R04184 globoside N-acetylhexosaminohydrolase
R04586 N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylhexosaminohydrolase
R04633 D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D- galactosyl-D-glucosylceramide galactohydrolase
R04856 sulfatide sulfohydrolase
R05105 3'-phosphoadenylylsulfate:digalactosylceramide 3'-sulfotransferase
R05112 Gal-beta1->3GalNAc-beta1->4Gal-beta1->4Glc-beta1->1'Cer (GA1) galactohydrolase
R06516 sphingosine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)
R06517 acyl-CoA:sphingosine N-acyltransferase
R06518 N-acylsphingosine amidohydrolase
R06519 dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (4,5-dehydrogenating)
R06520 3-sn-phosphatidate phosphohydrolase
R06521 3-sn-phosphatidate phosphohydrolase
R06522 3-sn-phosphatidate phosphohydrolase
R06525 sphinganine,ferrocytochrome b5:oxygen oxidoreductase (C4-hydroxylating)
R06526 dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (C4-hydroxylating)
R06527 acyl-CoA: phytosphingosine N-acyltransferase
R06528 phytoceramide amidohydrolase
R08969 ceramide:phosphatidylcholine cholinephosphotransferase
R12960 3'-phosphoadenylyl-sulfate:lactosylceramide 3'-sulfotransferase
R12961 lactosylceramide-sulfate sulfohydrolase
R12962 UDP-N-acetyl-D-galactosamine:lactosylceramide-sulfate N-acetyl-D-galactrosaminyltransferase
R12963 gangliotriaosylceramide-II3-sulfate N-acetylgalactosaminohydrolase
R13178 D-glucosylsphingosine glucohydrolase
R13179 psychosine galactohydrolase
Compound C01120 Sphinganine 1-phosphate
C03405 Lactosylceramide sulfate
C03640 Sphingosyl-phosphocholine
C04737 alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884 N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911 D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681 Ceramide 2-aminoethylphosphonate
C06062 Ceramide phosphoethanolamine
C06124 Sphingosine 1-phosphate
C06127 Digalactosylceramide sulfate
C22467 Gangliotriaosylceramide-II3 sulfate
Reference Authors Merrill AH Jr.
Title De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
Journal Reference Authors Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
Title Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
Journal Reference Authors Hannun YA, Luberto C, Argraves KM.
Title Enzymes of sphingolipid metabolism: from modular to integrative signaling.
Journal Reference Authors Merrill AH Jr, Wang E.
Title Enzymes of ceramide biosynthesis.
Journal Reference Authors Hirschberg K, Rodger J, Futerman AH.
Title The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
Journal Reference Authors Dickson RC, Lester RL.
Title Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
Journal Related rn00260 Glycine, serine and threonine metabolism
rn00601 Glycosphingolipid biosynthesis - lacto and neolacto series
rn00603 Glycosphingolipid biosynthesis - globo and isoglobo series
rn00604 Glycosphingolipid biosynthesis - ganglio series
KO pathway LinkDB All DBs
