KEGG   REACTION: R00114
Entry
R00114                      Reaction                               
Name
L-glutamate:NADP+ oxidoreductase (transaminating)
Definition
2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+
Equation
2 C00025 + C00006 <=> C00064 + C00026 + C00005 + C00080
Comment
two-step reaction (see R00256+R00248)
Reaction class
RC00001  C00005_C00006
RC00006  C00025_C00026
RC00010  C00025_C00064
Enzyme
1.4.1.13
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.13
     R00114  2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+
Orthology
K00265  glutamate synthase (NADPH) large chain [EC:1.4.1.13]
K00266  glutamate synthase (NADPH) small chain [EC:1.4.1.13]
Other DBs
RHEA: 15504
LinkDB

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