KEGG   REACTION: R00894
Entry
R00894                      Reaction                               
Name
L-glutamate:L-cysteine gamma-ligase (ADP-forming)
Definition
ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine
Equation
C00002 + C00025 + C00097 <=> C00008 + C00009 + C00669
Reaction class
RC00002  C00002_C00008
RC00064  C00097_C00669
RC00090  C00025_C00669
Enzyme
6.3.2.2
Pathway
rn00480  Glutathione metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00118  Glutathione biosynthesis, glutamate => glutathione
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2
     R00894  ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine
Orthology
K01919  glutamate--cysteine ligase [EC:6.3.2.2]
K06048  glutamate---cysteine ligase / carboxylate-amine ligase [EC:6.3.2.2 6.3.-.-]
K11204  glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205  glutamate--cysteine ligase regulatory subunit
Other DBs
RHEA: 13288
LinkDB

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