KEGG   REACTION: R01775
Entry
R01775                      Reaction                               
Name
L-homoserine:NADP+ oxidoreductase
Definition
L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+
Equation
C00263 + C00006 <=> C00441 + C00005 + C00080
Comment
NAD+ (see R01773)
Reaction class
RC00001  C00005_C00006
RC00087  C00263_C00441
Enzyme
1.1.1.3
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00270  Cysteine and methionine metabolism
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
Module
M00017  Methionine biosynthesis, aspartate => homoserine => methionine
M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3
     R01775  L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+
Orthology
K00003  homoserine dehydrogenase [EC:1.1.1.3]
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Other DBs
RHEA: 15764
LinkDB

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