KEGG   REACTION: R01804
Entry
R01804                      Reaction                               
Name
phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)
Definition
N-Acetylneuraminate + Orthophosphate <=> N-Acetyl-D-mannosamine + Phosphoenolpyruvate + H2O
Equation
C00270 + C00009 <=> C00645 + C00074 + C00001
Reaction class
RC00159  C00270_C00645
Enzyme
2.5.1.56
Pathway
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Module
M00922  CMP-Neu5Ac biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.56
     R01804  N-Acetylneuraminate + Orthophosphate <=> N-Acetyl-D-mannosamine + Phosphoenolpyruvate + H2O
Orthology
K01654  N-acetylneuraminate synthase [EC:2.5.1.56]
Other DBs
RHEA: 19276
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