REACTION: R01936
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Entry
R01936 Reaction
Name
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)
Definition
Oxaloglutarate <=> 2-Oxoadipate + CO2
Equation
C05533
<=>
C00322
+
C00011
Comment
the second step of two-step reaction (see
R01934, R04862+R01936
)
following after
R04862
Reaction class
RC00626
C00322_C05533
Enzyme
1.1.1.87
1.1.1.286
Pathway
rn01210
2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.87
R01936 Oxaloglutarate <=> 2-Oxoadipate + CO2
1.1.1.286
R01936 Oxaloglutarate <=> 2-Oxoadipate + CO2
BRITE hierarchy
Orthology
K05824
homoisocitrate dehydrogenase [EC:
1.1.1.87
]
K10978
methanogen homoisocitrate dehydrogenase [EC:
1.1.1.87
1.1.1.-]
K17753
isocitrate--homoisocitrate dehydrogenase [EC:
1.1.1.286
]
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