Entry
Name
nicotinamide ribonucleotide phosphohydrolase
Definition
Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
Equation
Reaction class
Enzyme
Pathway
rn00760 Nicotinate and nicotinamide metabolism
Brite
Enzymatic reactions [BR:br08201 ]
3. Hydrolase reactions
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.5
R02323 Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
3.1.3.-
R02323 Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
IUBMB reaction hierarchy [BR:br08202 ]
3. Hydrolase reactions
3.1.3.5
R07297 5'-Ribonucleotide <=> Ribonucleoside
R02323 Nicotinamide D-ribonucleotide <=> Nicotinamide-beta-riboside
BRITE hierarchy
Orthology
K18550 IMP and pyridine-specific 5'-nucleotidase [EC:3.1.3.99 3.1.3.-]
K18551 pyrimidine and pyridine-specific 5'-nucleotidase [EC:3.1.3.-]
Reference
Authors
Bogan KL, Evans C, Belenky P, Song P, Burant CF, Kennedy R, Brenner C
Title
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.
Journal
Other DBs
LinkDB
All DBs