KEGG   REACTION: R02323
Entry
R02323                      Reaction                               
Name
nicotinamide ribonucleotide phosphohydrolase
Definition
Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
Equation
Reaction class
RC00017  C00455_C03150
Enzyme
3.1.3.5         3.1.3.-
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.5
     R02323  Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
    3.1.3.-
     R02323  Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.1.3.5
   R07297  5'-Ribonucleotide <=> Ribonucleoside
    R02323  Nicotinamide D-ribonucleotide <=> Nicotinamide-beta-riboside
Orthology
K01081  5'-nucleotidase [EC:3.1.3.5]
K02566  5'-nucleotidase [EC:3.1.3.5]
K03787  5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
K08693  2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5]
K11751  5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]
K18550  IMP and pyridine-specific 5'-nucleotidase [EC:3.1.3.99 3.1.3.-]
K18551  pyrimidine and pyridine-specific 5'-nucleotidase [EC:3.1.3.-]
K19970  5'-nucleotidase [EC:3.1.3.5]
Reference
1  [PMID:19846558]
  Authors
Bogan KL, Evans C, Belenky P, Song P, Burant CF, Kennedy R, Brenner C
  Title
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.
  Journal
J Biol Chem 284:34861-9 (2009)
DOI:10.1074/jbc.M109.056689
Other DBs
RHEA: 30818
LinkDB

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