KEGG   REACTION: R02519
Entry
R02519                      Reaction                               
Name
homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
Definition
Homogentisate + Oxygen <=> 4-Maleylacetoacetate
Equation
C00544 + C00007 <=> C01036
Reaction class
RC00737  C00544_C01036
Enzyme
1.13.11.5
Pathway
rn00350  Tyrosine metabolism
rn00643  Styrene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00044  Tyrosine degradation, tyrosine => homogentisate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.5
     R02519  Homogentisate + Oxygen <=> 4-Maleylacetoacetate
Orthology
K00451  homogentisate 1,2-dioxygenase [EC:1.13.11.5]
Other DBs
RHEA: 15452
LinkDB

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