KEGG   REACTION: R04001
Entry
R04001                      Reaction                               
Name
3-isopropylmalate hydro-lyase
Definition
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
Equation
C04411 <=> C02631 + C00001
Reaction class
RC01046  C02631_C04411
Enzyme
4.2.1.33
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Module
M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33
     R04001  (2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
Orthology
K01702  3-isopropylmalate dehydratase [EC:4.2.1.33]
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
K21359  3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.170]
Other DBs
RHEA: 10679
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