KEGG   REACTION: R04364
Entry
R04364                      Reaction                               
Name
acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase
Definition
2,3,4,5-Tetrahydrodipicolinate + Acetyl-CoA + H2O <=> N-Acetyl-L-2-amino-6-oxopimelate + CoA
Equation
Reaction class
RC00004  C00010_C00024
RC01136  C03972_C05539
Enzyme
2.3.1.89        2.3.1.-
Pathway
rn00261  Monobactam biosynthesis
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.89
     R04364  2,3,4,5-Tetrahydrodipicolinate + Acetyl-CoA + H2O <=> N-Acetyl-L-2-amino-6-oxopimelate + CoA
    2.3.1.-
     R04364  2,3,4,5-Tetrahydrodipicolinate + Acetyl-CoA + H2O <=> N-Acetyl-L-2-amino-6-oxopimelate + CoA
Orthology
K05822  tetrahydrodipicolinate N-acetyltransferase [EC:2.3.1.89]
K19107  putative acetyltransferase [EC:2.3.1.-]
Reference
1  [PMID:9294453]
  Authors
Liu L, Shaw PD
  Title
A possible role for acetylated intermediates in diaminopimelate and tabtoxinine-beta-lactam biosynthesis in Pseudomonas syringae pv. tabaci BR2.024.
  Journal
J Bacteriol 179:5922-7 (1997)
DOI:10.1128/JB.179.18.5922-5927.1997
Reference
2  [PMID:23135477]
  Authors
Hamed RB, Gomez-Castellanos JR, Henry L, Ducho C, McDonough MA, Schofield CJ
  Title
The enzymes of beta-lactam biosynthesis.
  Journal
Nat Prod Rep 30:21-107 (2013)
DOI:10.1039/c2np20065a
Other DBs
RHEA: 13088
LinkDB

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