| Entry |
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| Name |
5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate-lyase (L-glutamine-hydrolysing; 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide-forming)
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| Definition |
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + L-Glutamine <=> D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + L-Glutamate
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| Equation |
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| Comment |
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| Reaction class |
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| Enzyme |
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| Pathway |
| rn01110 | Biosynthesis of secondary metabolites |
| rn01230 | Biosynthesis of amino acids |
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| Module |
| M00026 | Histidine biosynthesis, PRPP => histidine |
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| Brite |
Enzymatic reactions [BR:br08201]
4. Lyase reactions
4.3 Carbon-nitrogen lyases
4.3.2 Amidine-lyases
4.3.2.10
R04558 N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + L-Glutamine <=> D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + L-Glutamate
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| Orthology |
| K02500 | imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] |
| K02501 | imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] |
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| Other DBs |
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| LinkDB |
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