tacr2 tachykinin receptor 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tacr2provided by ZNC
Official Full Name: tachykinin receptor 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-090312-188
See related: Ensembl:ENSDARG00000074509 AllianceGenome:ZFIN:ZDB-GENE-090312-188
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-1n9.11
Summary: Predicted to enable substance K receptor activity. Predicted to be involved in positive regulation of flagellated sperm motility. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane and sperm midpiece. Human ortholog(s) of this gene implicated in asthma. Orthologous to human TACR2 (tachykinin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (22964474..22971637)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (22834024..22841187)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables substance K receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables tachykinin receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of flagellated sperm motility	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in sperm midpiece	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: substance-K receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001327859.1 → NP_001314788.1 substance-K receptor

Status: VALIDATED

Source sequence(s)

BX530068

UniProtKB/TrEMBL

A0A8M1P8D8, F1QPL8

Related

ENSDARP00000117211.2, ENSDART00000142129.3

Conserved Domains (2) summary

pfam00001
Location:51 → 307

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:41 → 166

7tm_4; Olfactory receptor