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Slc19a1 solute carrier family 19 member 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100689407, updated on 8-Mar-2024

Summary

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Gene symbol
Slc19a1
Gene description
solute carrier family 19 member 1
See related
Ensembl:ENSCGRG00015019651
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
RFC1; RFC-1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613799.1 (802953..818714)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (261734996..261750276, complement)

NW_003613799.1Genomic Context describing neighboring genes Neighboring gene collagen type VI alpha 1 chain Neighboring gene poly(rC) binding protein 3 Neighboring gene cytochrome c-like Neighboring gene uncharacterized LOC113833353 Neighboring gene collagen type XVIII alpha 1 chain Neighboring gene uncharacterized LOC107978529

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake. Williams FM, et al. J Biol Chem, 1994 Feb 25. PMID 8119923
  2. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables folate:monoatomic anion antiporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables folic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methotrexate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in folate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methotrexate transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
reduced folate transporter
Names
58 kDa hydrophobic protein
Folate carrier protein
Folate transporter 1
Methotrexate uptake protein
plasma membrane folate antiporter SLC19A1
reduced folate carrier 1
solute carrier family 19 (folate transporter), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246831.1 → NP_001233760.1  reduced folate transporter

    See identical proteins and their annotated locations for NP_001233760.1

    Status: PROVISIONAL

    Source sequence(s)
    U03031
    UniProtKB/Swiss-Prot
    P42557
    Related
    ENSCGRP00015025903.1, ENSCGRT00015031758.2
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 518
    rfc; RFC reduced folate carrier

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613799.1 Reference CriGri_1.0 Primary Assembly

    Range
    802953..818714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007641316.4 → XP_007639506.1  reduced folate transporter isoform X1

    See identical proteins and their annotated locations for XP_007639506.1

    UniProtKB/Swiss-Prot
    G3H8Y7, P42557
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 518
    rfc; RFC reduced folate carrier

  2. XM_007641314.4 → XP_007639504.1  reduced folate transporter isoform X1

    See identical proteins and their annotated locations for XP_007639504.1

    UniProtKB/Swiss-Prot
    G3H8Y7, P42557
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 518
    rfc; RFC reduced folate carrier

  3. XM_007641311.4 → XP_007639501.1  reduced folate transporter isoform X1

    See identical proteins and their annotated locations for XP_007639501.1

    UniProtKB/Swiss-Prot
    G3H8Y7, P42557
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 518
    rfc; RFC reduced folate carrier

  4. XM_007641313.4 → XP_007639503.1  reduced folate transporter isoform X1

    See identical proteins and their annotated locations for XP_007639503.1

    UniProtKB/Swiss-Prot
    G3H8Y7, P42557
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 518
    rfc; RFC reduced folate carrier

  5. XM_027435323.2 → XP_027291124.1  reduced folate transporter isoform X2

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    261734996..261750276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42557.2 GenPept UniProtKB/Swiss-Prot:P42557

Gene LinkOut

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