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Plcb1 phospholipase C beta 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100751979, updated on 8-Mar-2024

Summary

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Gene symbol
Plcb1
Gene description
phospholipase C beta 1
Locus tag
I79_000439
See related
Ensembl:ENSCGRG00015010058
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
31
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613587.1 (3034049..3711702, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 6 NC_048599.1 (43177851..43856831, complement)

NW_003613587.1Genomic Context describing neighboring genes Neighboring gene NIF3-like protein 1 Neighboring gene phospholipase C beta 4 Neighboring gene 60S ribosomal protein L17-like Neighboring gene 60S ribosomal protein L39-like Neighboring gene uncharacterized LOC118239093 Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene hydroxyacid oxidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Names
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
phospholipase C, beta 1 (phosphoinositide-specific)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613587.1 Reference CriGri_1.0 Primary Assembly

    Range
    3034049..3711702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035447340.1 → XP_035303231.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C2MUM7, A0A8C2MXR9
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1172
    PLC-beta_C; PLC-beta C terminal

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048599.1 Alternate CriGri-PICRH-1.0

    Range
    43177851..43856831 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035446906.1 → XP_035302797.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X4

    UniProtKB/TrEMBL
    A0A8C2MXR9, A0A9J7KAX3
    Related
    ENSCGRP00015013307.2, ENSCGRT00015016283.2
    Conserved Domains (5) summary
    cd00275
    Location:654 → 773
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:293 → 620
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 125
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:130 → 280
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:980 → 1149
    PLC-beta_C; PLC-beta C terminal

  2. XM_027421690.2 → XP_027277491.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C2MUM7, A0A8C2MXR9
    Related
    ENSCGRP00015051135.1, ENSCGRT00015078867.1
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1172
    PLC-beta_C; PLC-beta C terminal

  3. XM_035446909.1 → XP_035302800.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X6

    UniProtKB/TrEMBL
    A0A8C2MXR9, A0A9J7H3Q5
    Conserved Domains (5) summary
    cd00275
    Location:576 → 695
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 542
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd16208
    Location:52 → 202
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:902 → 1071
    PLC-beta_C; PLC-beta C terminal
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain

  4. XM_035446908.1 → XP_035302799.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X6

    UniProtKB/TrEMBL
    A0A8C2MXR9, A0A9J7H3Q5
    Conserved Domains (5) summary
    cd00275
    Location:576 → 695
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 542
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd16208
    Location:52 → 202
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:902 → 1071
    PLC-beta_C; PLC-beta C terminal
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain

  5. XM_035446905.1 → XP_035302796.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    UniProtKB/TrEMBL
    A0A8C2MUL7, A0A9J7H4Q5
    Related
    ENSCGRP00015013330.2, ENSCGRT00015016312.2
    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    COG0419
    Location:893 → 1176
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  6. XM_027421691.2 → XP_027277492.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X5

    UniProtKB/TrEMBL
    A0A8C2MUL7, A0A9J7H4B7
    Related
    ENSCGRP00015013252.2, ENSCGRT00015016213.2
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  7. XM_035446907.1 → XP_035302798.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X5

    UniProtKB/TrEMBL
    A0A8C2MUL7, A0A9J7H4B7
    Related
    ENSCGRP00015013208.2, ENSCGRT00015016160.2
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal
Nucleotide Protein Strain
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