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Lta4h leukotriene A4 hydrolase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100753500, updated on 8-Mar-2024

Summary

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Gene symbol
Lta4h
Gene description
leukotriene A4 hydrolase
Locus tag
I79_007819
See related
Ensembl:ENSCGRG00015020222
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613849.1 (977372..1009823)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (159442394..159475211)

NW_003613849.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107979681 Neighboring gene transfer RNA aspartic acid (anticodon GUC) Neighboring gene histidine ammonia-lyase Neighboring gene amidohydrolase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epoxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables leukotriene-A4 hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leukotriene A-4 hydrolase
Names
Leukotriene A-4 hydrolase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613849.1 Reference CriGri_1.0 Primary Assembly

    Range
    977372..1009823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003501416.5 → XP_003501464.1  leukotriene A-4 hydrolase isoform X1

    See identical proteins and their annotated locations for XP_003501464.1

    UniProtKB/TrEMBL
    A0A3L7IHY9, A0A8C2LTY7
    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase

  2. XM_007642082.4 → XP_007640272.1  leukotriene A-4 hydrolase isoform X2

    See identical proteins and their annotated locations for XP_007640272.1

    UniProtKB/TrEMBL
    A0A8C2LTY7, A0A9J7F691
    Conserved Domains (3) summary
    cd09599
    Location:6 → 450
    M1_LTA4H; Peptidase M1 family contains leukotriene A4 hydrolase
    pfam01433
    Location:21 → 387
    Peptidase_M1; Peptidase family M1
    pfam09127
    Location:468 → 530
    Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    159442394..159475211
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027392631.2 → XP_027248432.1  leukotriene A-4 hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A3L7IHY9, A0A8C2LTY7
    Related
    ENSCGRP00015026679.1, ENSCGRT00015032681.2

  2. XM_027392632.2 → XP_027248433.1  leukotriene A-4 hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8C2LTY7, A0A9J7F691
Nucleotide Protein Strain
Heading Accession and Version

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