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Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100754096, updated on 8-Mar-2024

Summary

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Gene symbol
Pfkfb1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Locus tag
I79_006413
See related
Ensembl:ENSCGRG00015018571
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
17
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613780.1 (425886..479137)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) X NC_048604.1 (108861652..108915057, complement)

NW_003613780.1Genomic Context describing neighboring genes Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene trophinin Neighboring gene histone H3.3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Names
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613780.1 Reference CriGri_1.0 Primary Assembly

    Range
    425886..479137
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035454358.1 → XP_035310249.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A9J7H8L2, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:252 → 384
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 249
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_035454355.1 → XP_035310246.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H9E5, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_035454356.1 → XP_035310247.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H9E5, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_035454354.1 → XP_035310245.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A9J7H9G3, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:252 → 430
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 249
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_016974512.3 → XP_016830001.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H9E5, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_003500186.4 → XP_003500234.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    See identical proteins and their annotated locations for XP_003500234.1

    UniProtKB/TrEMBL
    A0A8C2MIH6, G3H7S5
    Conserved Domains (3) summary
    pfam00300
    Location:252 → 433
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 249
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:42 → 196
    AAA_33; AAA domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048604.1 Alternate CriGri-PICRH-1.0

    Range
    108861652..108915057 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035449881.1 → XP_035305772.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A9J7H8L2, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:252 → 384
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 249
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_035449878.1 → XP_035305769.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A9J7H9G3, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:252 → 430
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 249
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_027432032.2 → XP_027287833.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H9E5, G3H7S5
    Related
    ENSCGRP00015024462.2, ENSCGRT00015030013.2
    Conserved Domains (2) summary
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_027432031.2 → XP_027287832.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C2MIH6, G3H7S5
    Related
    ENSCGRP00015024508.2, ENSCGRT00015030069.2

  5. XM_035449880.1 → XP_035305771.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H9E5, G3H7S5
    Related
    ENSCGRP00015024478.1, ENSCGRT00015030033.2
    Conserved Domains (2) summary
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_035449879.1 → XP_035305770.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H9E5, G3H7S5
    Conserved Domains (2) summary
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein Strain
Heading Accession and Version

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