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Tyms thymidylate synthetase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100754276, updated on 8-Mar-2024

Summary

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Gene symbol
Tyms
Gene description
thymidylate synthetase
See related
Ensembl:ENSCGRG00015000262
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
7
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003616055.1 (39415..48797)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (461561669..461571042, complement)

NW_003616055.1Genomic Context describing neighboring genes Neighboring gene clusterin like 1 Neighboring gene enolase superfamily member 1 Neighboring gene nucleophosmin-like Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters. Aleidi SM, et al. J Biol Chem, 2015 Oct 2. PMID 26296893, Free PMC Article
  2. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thymidylate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dTMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thymidylate synthase
Names
Thymidylate synthase
thymidylate synthase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003616055.1 Reference CriGri_1.0 Primary Assembly

    Range
    39415..48797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003513643.5 → XP_003513691.1  thymidylate synthase

    See identical proteins and their annotated locations for XP_003513691.1

    UniProtKB/TrEMBL
    A0A061IFK8, G3IFY1
    Conserved Domains (1) summary
    cl19097
    Location:22 → 307
    TS_Pyrimidine_HMase; Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the ...

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    461561669..461571042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027398958.2 → XP_027254759.1  thymidylate synthase

    UniProtKB/TrEMBL
    A0A061IFK8, G3IFY1
    Related
    ENSCGRP00015000235.1, ENSCGRT00015000327.2
Nucleotide Protein Strain
Heading Accession and Version

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