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Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100755385, updated on 11-Apr-2024

Summary

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Gene symbol
Hmgcl
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
Locus tag
I79_012073
See related
Ensembl:ENSCGRG00015019415
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614105.1 (330192..345067, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (17346058..17361573, complement)

NW_003614105.1Genomic Context describing neighboring genes Neighboring gene lysophospholipase 2 Neighboring gene 60S ribosomal protein L32-like Neighboring gene UDP-galactose-4-epimerase Neighboring gene alpha-L-fucosidase 1 Neighboring gene cannabinoid receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase
Hydroxymethylglutaryl-CoA lyase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614105.1 Reference CriGri_1.0 Primary Assembly

    Range
    330192..345067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035457435.1 → XP_035313326.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C2LKL8
    Conserved Domains (1) summary
    cl21457
    Location:17 → 325
    TIM; TIM-like beta/alpha barrel domains

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    17346058..17361573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027399712.2 → XP_027255513.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C2LKL8
    Related
    ENSCGRP00015048397.1, ENSCGRT00015075424.1
    Conserved Domains (1) summary
    cl21457
    Location:17 → 325
    TIM; TIM-like beta/alpha barrel domains

  2. XM_027399711.2 → XP_027255512.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A9J7FCZ1
    Related
    ENSCGRP00015025584.2, ENSCGRT00015031367.2

  3. XM_027399713.2 → XP_027255514.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A9J7FAV1

  4. XM_035439511.1 → XP_035295402.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X5

    UniProtKB/TrEMBL
    A0A9J7GN41
    Conserved Domains (1) summary
    cd07938
    Location:1 → 224
    DRE_TIM_HMGL; 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain
Nucleotide Protein Strain
Heading Accession and Version

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