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Aldh18a1 aldehyde dehydrogenase 18 family member A1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100755485, updated on 8-Mar-2024

Summary

Gene symbol
Aldh18a1
Gene description
aldehyde dehydrogenase 18 family member A1
See related
Ensembl:ENSCGRG00015025603
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614476.1 (44743..75634)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 3 NC_048596.1 (20998018..21032526)

NW_003614476.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103164176 Neighboring gene tectonic family member 3 Neighboring gene sorbin and SH3 domain containing 1 Neighboring gene PDZ and LIM domain 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glutamate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glutamate-5-semialdehyde dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proline biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
delta-1-pyrroline-5-carboxylate synthase
Names
Delta-1-pyrroline-5-carboxylate synthetase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614476.1 Reference CriGri_1.0 Primary Assembly

    Range
    44743..75634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007648697.3XP_007646887.1  delta-1-pyrroline-5-carboxylate synthase isoform X1

    See identical proteins and their annotated locations for XP_007646887.1

    UniProtKB/TrEMBL
    G3HXX8
    Conserved Domains (3) summary
    TIGR01092
    Location:64793
    P5CS; delta l-pyrroline-5-carboxylate synthetase
    cd07079
    Location:364767
    ALDH_F18-19_ProA-GPR; Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19
    cd04256
    Location:63354
    AAK_P5CS_ProBA; AAK_P5CS_ProBA: Glutamate-5-kinase (G5K) domain of the bifunctional delta 1-pyrroline-5-carboxylate synthetase (P5CS), composed of an N-terminal G5K (ProB) and a C-terminal glutamyl 5- phosphate reductase (G5PR, ProA), the first and second enzyme ...
  2. XM_003508062.4XP_003508110.1  delta-1-pyrroline-5-carboxylate synthase isoform X2

    See identical proteins and their annotated locations for XP_003508110.1

    UniProtKB/TrEMBL
    A0A061IBJ4
    Conserved Domains (1) summary
    cl25378
    Location:64791
    ProB; Glutamate 5-kinase [Amino acid transport and metabolism]

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048596.1 Alternate CriGri-PICRH-1.0

    Range
    20998018..21032526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027407359.2XP_027263160.1  delta-1-pyrroline-5-carboxylate synthase isoform X1

    UniProtKB/TrEMBL
    G3HXX8
    Related
    ENSCGRP00015033956.1, ENSCGRT00015041435.2
  2. XM_027407360.2XP_027263161.1  delta-1-pyrroline-5-carboxylate synthase isoform X2

    UniProtKB/TrEMBL
    A0A061IBJ4
    Related
    ENSCGRP00015050693.1, ENSCGRT00015060226.1