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Nos1 nitric oxide synthase 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100758127, updated on 8-Mar-2024

Summary

Gene symbol
Nos1
Gene description
nitric oxide synthase 1
Locus tag
I79_001206
See related
Ensembl:ENSCGRG00015002270
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
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Genomic context

See Nos1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
28
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613605.1 (2299722..2378477, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (97778360..97857401)

NW_003613605.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA40 Neighboring gene kinase suppressor of ras 2 Neighboring gene uncharacterized LOC118238652 Neighboring gene replication factor C subunit 5

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in nitric oxide biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
nitric oxide synthase, brain
Names
Nitric oxide synthase, brain
nitric oxide synthase 1 (neuronal)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613605.1 Reference CriGri_1.0 Primary Assembly

    Range
    2299722..2378477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035457590.1XP_035313481.1  nitric oxide synthase, brain

    UniProtKB/TrEMBL
    A0A8C2LI30, A0A9J7K8J0
    Conserved Domains (4) summary
    cd06202
    Location:10301433
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:300711
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:757964
    Flavodoxin_1

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    97778360..97857401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035444176.1XP_035300067.1  nitric oxide synthase, brain

    UniProtKB/TrEMBL
    A0A8C2LI30, A0A9J7K8J0
    Related
    ENSCGRP00015003174.1, ENSCGRT00015003929.2
    Conserved Domains (4) summary
    cd06202
    Location:10301433
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:300711
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:757964
    Flavodoxin_1