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Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100761571, updated on 8-Mar-2024

Summary

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Gene symbol
Pfkfb4
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
See related
Ensembl:ENSCGRG00015014653
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
15
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614047.1 (185120..224333)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (217103602..217142867)

NW_003614047.1Genomic Context describing neighboring genes Neighboring gene collagen type VII alpha 1 chain Neighboring gene urocortin 2 Neighboring gene shisa family member 5 Neighboring gene three prime repair exonuclease 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614047.1 Reference CriGri_1.0 Primary Assembly

    Range
    185120..224333
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007644780.4 → XP_007642970.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X3

    UniProtKB/TrEMBL
    A0A9J7FWB6
    Conserved Domains (3) summary
    pfam00300
    Location:223 → 406
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:6 → 220
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:12 → 167
    AAA_33; AAA domain

  2. XM_007644781.4 → XP_007642971.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X2

    UniProtKB/TrEMBL
    A0A9J7FY20

  3. XM_003504239.5 → XP_003504287.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1

    See identical proteins and their annotated locations for XP_003504287.1

    UniProtKB/TrEMBL
    G3HKP6
    Conserved Domains (3) summary
    pfam00300
    Location:252 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 249
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:41 → 196
    AAA_33; AAA domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    217103602..217142867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027414621.2 → XP_027270422.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X3

    UniProtKB/TrEMBL
    A0A9J7FWB6
    Related
    ENSCGRP00015019148.2, ENSCGRT00015023602.2

  2. XM_027414620.2 → XP_027270421.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X2

    UniProtKB/TrEMBL
    A0A9J7FY20
    Related
    ENSCGRP00015019128.2, ENSCGRT00015023580.2

  3. XM_027414619.2 → XP_027270420.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1

    UniProtKB/TrEMBL
    G3HKP6
    Related
    ENSCGRP00015050367.1, ENSCGRT00015048541.1
Nucleotide Protein Strain
Heading Accession and Version

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