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Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100762235, updated on 8-Mar-2024

Summary

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Gene symbol
Hmgcs1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
Ensembl:ENSCGRG00015020108
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614106.1 (1047061..1066846)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (337097439..337117278)

NW_003614106.1Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine ligand 28 Neighboring gene uncharacterized LOC100761946 Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene zinc finger protein 131

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic
Names
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614106.1 Reference CriGri_1.0 Primary Assembly

    Range
    1047061..1066846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007645446.3 → XP_007643636.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for XP_007643636.1

    UniProtKB/Swiss-Prot
    P13704
    UniProtKB/TrEMBL
    G3HMY0
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 469
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_003504950.5 → XP_003504998.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for XP_003504998.1

    UniProtKB/Swiss-Prot
    P13704
    UniProtKB/TrEMBL
    G3HMY0
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 469
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    337097439..337117278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027401400.2 → XP_027257201.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/Swiss-Prot
    P13704
    UniProtKB/TrEMBL
    G3HMY0

  2. XM_027401401.2 → XP_027257202.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/Swiss-Prot
    P13704
    UniProtKB/TrEMBL
    G3HMY0
    Related
    ENSCGRP00015026537.1, ENSCGRT00015032510.2
Nucleotide Protein Strain
Heading Accession and Version

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