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Dnmt1 DNA methyltransferase 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100762713, updated on 11-Apr-2024

Summary

Gene symbol
Dnmt1
Gene description
DNA methyltransferase 1
Locus tag
I79_005894
See related
Ensembl:ENSCGRG00015024505
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
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Genomic context

Location:
chromosome: 4
Exon count:
42
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613752.1 (1242667..1313816)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (133776279..133822931, complement)

NW_003613752.1Genomic Context describing neighboring genes Neighboring gene intercellular adhesion molecule 1 Neighboring gene mitochondrial ribosomal protein L4 Neighboring gene uncharacterized LOC113835258 Neighboring gene U6 spliceosomal RNA Neighboring gene sphingosine-1-phosphate receptor 2 Neighboring gene suppressor of SWI4 1 homolog Neighboring gene small nucleolar RNA U105B Neighboring gene eukaryotic translation initiation factor 3 subunit G Neighboring gene purinergic receptor P2Y11

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA (cytosine-5-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
DNA (cytosine-5)-methyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613752.1 Reference CriGri_1.0 Primary Assembly

    Range
    1242667..1313816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016974336.3XP_016829825.1  DNA (cytosine-5)-methyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    G3H6D9
  2. XM_016974337.1XP_016829826.1  DNA (cytosine-5)-methyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    A0A061I455
  3. XM_016974335.3XP_016829824.1  DNA (cytosine-5)-methyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    G3H6D9
  4. XM_035454072.1XP_035309963.1  DNA (cytosine-5)-methyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    G3H6D9
    Conserved Domains (6) summary
    cd04711
    Location:9531088
    BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
    cd04760
    Location:742865
    BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
    pfam02008
    Location:632678
    zf-CXXC; CXXC zinc finger domain
    pfam06464
    Location:1486
    DMAP_binding; DMAP1-binding Domain
    cl30459
    Location:11251336
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
    pfam12047
    Location:388521
    DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    133776279..133822931 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027411471.2XP_027267272.1  DNA (cytosine-5)-methyltransferase 1 isoform X4

    UniProtKB/TrEMBL
    A0A061I455, A0A9J7FUZ5
    Related
    ENSCGRP00015032899.2, ENSCGRT00015040130.2
  2. XM_027411473.2XP_027267274.1  DNA (cytosine-5)-methyltransferase 1 isoform X6

    UniProtKB/TrEMBL
    A0A061I455, A0A9J7FV67
  3. XM_035443493.1XP_035299384.1  DNA (cytosine-5)-methyltransferase 1 isoform X5

    UniProtKB/TrEMBL
    A0A061I455, A0A9J7GYE0
    Related
    ENSCGRP00015032974.2, ENSCGRT00015040221.2
    Conserved Domains (6) summary
    COG0270
    Location:11251579
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd04711
    Location:9531088
    BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
    cd04760
    Location:742865
    BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
    pfam02008
    Location:632678
    zf-CXXC; CXXC zinc finger domain
    pfam06464
    Location:1486
    DMAP_binding; DMAP1-binding Domain
    pfam12047
    Location:388521
    DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain
  4. XM_027411474.2XP_027267275.1  DNA (cytosine-5)-methyltransferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A061I455, A0A9J7FT78