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Alox12 arachidonate 12-lipoxygenase, 12S type [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100764620, updated on 8-Mar-2024

Summary

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Gene symbol
Alox12
Gene description
arachidonate 12-lipoxygenase, 12S type
Locus tag
I79_002783
See related
Ensembl:ENSCGRG00015006647
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
14
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613643.1 (2283689..2297478, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (84067242..84078962, complement)

NW_003613643.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C17orf49 homolog Neighboring gene uncharacterized LOC113832503 Neighboring gene microRNA mir-195 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene cyclin-dependent kinases regulatory subunit 1-like Neighboring gene arachidonate 15-lipoxygenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables linoleate 13S-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polyunsaturated fatty acid lipoxygenase ALOX12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613643.1 Reference CriGri_1.0 Primary Assembly

    Range
    2283689..2297478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027388890.2 → XP_027244691.1  polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1

    UniProtKB/TrEMBL
    G3GYA8

  2. XM_035439714.1 → XP_035295605.1  polyunsaturated fatty acid lipoxygenase ALOX12 isoform X2

    UniProtKB/TrEMBL
    G3GYA8
    Conserved Domains (1) summary
    pfam00305
    Location:58 → 497
    Lipoxygenase

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048600.1 Alternate CriGri-PICRH-1.0

    Range
    84067242..84078962 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027426936.2 → XP_027282737.1  polyunsaturated fatty acid lipoxygenase ALOX12 isoform X3

    UniProtKB/TrEMBL
    A0A8C2MG18, A0A9J7JYW8
    Related
    ENSCGRP00015008573.1, ENSCGRT00015010553.2

  2. XM_035447811.1 → XP_035303702.1  polyunsaturated fatty acid lipoxygenase ALOX12 isoform X4

    UniProtKB/TrEMBL
    A0A8C2MG18, A0A9J7H661
    Conserved Domains (2) summary
    pfam00305
    Location:221 → 654
    Lipoxygenase
    cl00011
    Location:2 → 111
    PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
Nucleotide Protein Strain
Heading Accession and Version

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