U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Setdb1 SET domain bifurcated histone lysine methyltransferase 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100765697, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Setdb1
Gene description
SET domain bifurcated histone lysine methyltransferase 1
Locus tag
I79_004581
See related
Ensembl:ENSCGRG00015022520
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
23
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613699.1 (2044815..2083002)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (61138259..61177169)

NW_003613699.1Genomic Context describing neighboring genes Neighboring gene aryl hydrocarbon receptor nuclear translocator Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like Neighboring gene cortexin domain containing 2 Neighboring gene ceramide synthase 2 Neighboring gene annexin A9 Neighboring gene MINDY lysine 48 deubiquitinase 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heterochromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA methylation-dependent heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
histone-lysine N-methyltransferase SETDB1
Names
Histone-lysine N-methyltransferase SETDB1
SET domain bifurcated 1
histone-lysine N-methyltransferase SETDB1-like protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613699.1 Reference CriGri_1.0 Primary Assembly

    Range
    2044815..2083002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027418592.2 → XP_027274393.1  histone-lysine N-methyltransferase SETDB1 isoform X1

    UniProtKB/TrEMBL
    A0A2Z6LC65, G3H2X6
    Conserved Domains (6) summary
    smart00391
    Location:438 → 513
    MBD; Methyl-CpG binding domain
    cd10517
    Location:515 → 712
    SET_SETDB1; SET domain (including pre-SET and post-SET domains) found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cl40432
    Location:1042 → 1131
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam18300
    Location:40 → 97
    DUF5604; Domain of unknown function (DUF5604)
    cd20382
    Location:107 → 188
    Tudor_SETDB1_rpt1; first Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cd21181
    Location:195 → 248
    Tudor_SETDB1_rpt2; second Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins

  2. XM_003498654.5 → XP_003498702.3  histone-lysine N-methyltransferase SETDB1 isoform X1

    UniProtKB/TrEMBL
    A0A2Z6LC65, G3H2X6
    Conserved Domains (6) summary
    smart00391
    Location:438 → 513
    MBD; Methyl-CpG binding domain
    cd10517
    Location:515 → 712
    SET_SETDB1; SET domain (including pre-SET and post-SET domains) found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cl40432
    Location:1042 → 1131
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam18300
    Location:40 → 97
    DUF5604; Domain of unknown function (DUF5604)
    cd20382
    Location:107 → 188
    Tudor_SETDB1_rpt1; first Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cd21181
    Location:195 → 248
    Tudor_SETDB1_rpt2; second Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    61138259..61177169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027393617.2 → XP_027249418.1  histone-lysine N-methyltransferase SETDB1 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LUV4, G3H2X6

  2. XM_027393616.2 → XP_027249417.1  histone-lysine N-methyltransferase SETDB1 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LUV4, G3H2X6
    Related
    ENSCGRP00015030012.2, ENSCGRT00015036682.2

  3. XM_027393618.2 → XP_027249419.1  histone-lysine N-methyltransferase SETDB1 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LUV4, G3H2X6

  4. XM_035450798.1 → XP_035306689.1  histone-lysine N-methyltransferase SETDB1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7HAZ1
    Conserved Domains (5) summary
    smart00391
    Location:591 → 666
    MBD; Methyl-CpG binding domain
    cl40432
    Location:668 → 771
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam18300
    Location:193 → 250
    DUF5604; Domain of unknown function (DUF5604)
    cd20382
    Location:260 → 341
    Tudor_SETDB1_rpt1; first Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cd21181
    Location:348 → 401
    Tudor_SETDB1_rpt2; second Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins

  5. XM_035450797.1 → XP_035306688.1  histone-lysine N-methyltransferase SETDB1 isoform X1

    UniProtKB/TrEMBL
    A0A2Z6LC65, G3H2X6
    Conserved Domains (6) summary
    smart00391
    Location:438 → 513
    MBD; Methyl-CpG binding domain
    cd10517
    Location:515 → 712
    SET_SETDB1; SET domain (including pre-SET and post-SET domains) found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cl40432
    Location:1042 → 1131
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam18300
    Location:40 → 97
    DUF5604; Domain of unknown function (DUF5604)
    cd20382
    Location:107 → 188
    Tudor_SETDB1_rpt1; first Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins
    cd21181
    Location:195 → 248
    Tudor_SETDB1_rpt2; second Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.