Hsd17b8 hydroxysteroid 17-beta dehydrogenase 8 [Cricetulus griseus (Chinese hamster)] - Gene

Summary

Gene symbol: Hsd17b8
Gene description: hydroxysteroid 17-beta dehydrogenase 8
Locus tag: I79_013175
See related: Ensembl:ENSCGRG00015028286
Gene type: protein coding
RefSeq status: MODEL
Organism: Cricetulus griseus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
104	current	CriGri_1.0 (GCF_000223135.1)	Unplaced Scaffold	NW_003614196.1 (695626..697726, complement)
104	current	CriGri-PICRH-1.0 (GCF_003668045.3)	1 Unlocalized Scaffold	NW_023276806.1 (230071051..230073147, complement)

NW_003614196.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

H2-Ke6 (e-PCR), detects polymorphism
- UniSTS:463413

MARC_5283-5284:991939549:1 (e-PCR)
- UniSTS:231147

MARC_5283-5284:996690262:1 (e-PCR)
- UniSTS:231147

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables estradiol 17-beta-dehydrogenase [NAD(P)] activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in estrogen biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: estradiol 17-beta-dehydrogenase 8

Names: Estradiol 17-beta-dehydrogenase 8; estradiol 17-beta-dehydrogenase 8-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

NW_003614196.1 Reference CriGri_1.0 Primary Assembly

Range

695626..697726 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003505898.4 → XP_003505946.1 estradiol 17-beta-dehydrogenase 8 isoform X1

See identical proteins and their annotated locations for XP_003505946.1

UniProtKB/TrEMBL

A0A061ILV4, G3HQR9

Conserved Domains (1) summary

cd05333
Location:11 → 258

BKR_SDR_c; beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs
XM_035458024.1 → XP_035313915.1 estradiol 17-beta-dehydrogenase 8 isoform X2

UniProtKB/TrEMBL

A0A9J7KES2

Conserved Domains (1) summary

cl21454
Location:11 → 219

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RNA

XR_001727407.1 RNA Sequence

Alternate CriGri-PICRH-1.0

Genomic

NW_023276806.1 Alternate CriGri-PICRH-1.0

Range

230071051..230073147 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_027388717.2 → XP_027244518.1 estradiol 17-beta-dehydrogenase 8 isoform X1

UniProtKB/TrEMBL

A0A061ILV4, G3HQR9

Related

ENSCGRP00015037767.1, ENSCGRT00015046042.2
XM_035451978.1 → XP_035307869.1 estradiol 17-beta-dehydrogenase 8 isoform X2

UniProtKB/TrEMBL

A0A9J7KES2

Conserved Domains (1) summary

cl21454
Location:11 → 219

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins