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Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100767336, updated on 8-Mar-2024

Summary

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Gene symbol
Mthfd1l
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
See related
Ensembl:ENSCGRG00015008979
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
28
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613604.1 (685605..861602)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (281697495..281874524)

NW_003613604.1Genomic Context describing neighboring genes Neighboring gene iodotyrosine deiodinase Neighboring gene pleckstrin homology and RhoGEF domain containing G1 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC103161639 Neighboring gene U1 spliceosomal RNA Neighboring gene U8 small nucleolar RNA Neighboring gene A-kinase anchoring protein 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables formate-tetrahydrofolate ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
monofunctional C1-tetrahydrofolate synthase, mitochondrial
Names
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613604.1 Reference CriGri_1.0 Primary Assembly

    Range
    685605..861602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003495871.5 → XP_003495919.1  monofunctional C1-tetrahydrofolate synthase, mitochondrial

    See identical proteins and their annotated locations for XP_003495919.1

    UniProtKB/TrEMBL
    G3GU10
    Conserved Domains (4) summary
    PRK14166
    Location:79 → 336
    PRK14166; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional
    PLN02759
    Location:349 → 975
    PLN02759; Formate--tetrahydrofolate ligase
    pfam00763
    Location:71 → 177
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
    cl21454
    Location:190 → 332
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    281697495..281874524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027400996.2 → XP_027256797.1  monofunctional C1-tetrahydrofolate synthase, mitochondrial

    UniProtKB/TrEMBL
    G3GU10
    Related
    ENSCGRP00015012230.1, ENSCGRT00015014993.2
Nucleotide Protein Strain
Heading Accession and Version

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