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Plcg1 phospholipase C gamma 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100769697, updated on 8-Mar-2024

Summary

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Gene symbol
Plcg1
Gene description
phospholipase C gamma 1
Locus tag
I79_015398
See related
Ensembl:ENSCGRG00015023643
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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See Plcg1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
31
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614415.1 (301196..316070)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 6 NC_048599.1 (18749566..18780068, complement)

NW_003614415.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC113836365 Neighboring gene cyclic AMP-dependent transcription factor ATF-4-like Neighboring gene DNA topoisomerase I Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene lipin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Names
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614415.1 Reference CriGri_1.0 Primary Assembly

    Range
    301196..316070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003507684.5 → XP_003507732.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

    See identical proteins and their annotated locations for XP_003507732.1

    UniProtKB/TrEMBL
    G3HWN7
    Conserved Domains (8) summary
    smart00149
    Location:842 → 957
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:975 → 1099
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:208 → 354
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:551 → 653
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:433 → 537
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:679 → 738
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:752 → 821
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cl17171
    Location:1 → 39
    PH-like; Pleckstrin homology-like domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048599.1 Alternate CriGri-PICRH-1.0

    Range
    18749566..18780068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035446887.1 → XP_035302778.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X3

    UniProtKB/TrEMBL
    A0A9J7H1N0, G3HWN7
    Conserved Domains (10) summary
    smart00149
    Location:954 → 1069
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1087 → 1211
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:320 → 466
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:663 → 765
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:545 → 649
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:791 → 850
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:864 → 933
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd16214
    Location:156 → 306
    EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
    cl17171
    Location:489 → 523
    PH-like; Pleckstrin homology-like domain

  2. XM_035446888.1 → XP_035302779.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X4

    UniProtKB/TrEMBL
    A0A9J7H0U3, G3HWN7
    Related
    ENSCGRP00015031344.2, ENSCGRT00015038294.2
    Conserved Domains (11) summary
    smart00149
    Location:955 → 1070
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1088 → 1212
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:321 → 467
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:664 → 766
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:546 → 650
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:792 → 851
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:865 → 934
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd15898
    Location:156 → 185
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:156 → 307
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl17171
    Location:490 → 524
    PH-like; Pleckstrin homology-like domain

  3. XM_035446886.1 → XP_035302777.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2

    UniProtKB/TrEMBL
    A0A9J7K9A8, G3HWN7
    Conserved Domains (11) summary
    smart00149
    Location:955 → 1070
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1088 → 1212
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:321 → 467
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:664 → 766
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:546 → 650
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:792 → 851
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:865 → 934
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd15898
    Location:156 → 185
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:156 → 307
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl17171
    Location:490 → 524
    PH-like; Pleckstrin homology-like domain

  4. XM_035446889.1 → XP_035302780.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X5

    UniProtKB/TrEMBL
    A0A8C2QIV8, G3HWN7
    Conserved Domains (10) summary
    smart00149
    Location:954 → 1069
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1087 → 1211
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:320 → 466
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:663 → 765
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:545 → 649
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:791 → 850
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:864 → 933
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd16214
    Location:156 → 306
    EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
    cl17171
    Location:489 → 523
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein Strain
Heading Accession and Version

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