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Dnmt3a DNA methyltransferase 3 alpha [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100771064, updated on 11-Apr-2024

Summary

Gene symbol
Dnmt3a
Gene description
DNA methyltransferase 3 alpha
Locus tag
I79_002537
See related
Ensembl:ENSCGRG00015026756
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
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Genomic context

Location:
chromosome: 7
Exon count:
24
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613640.1 (774575..893391, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (14683412..14802579)

NW_003613640.1Genomic Context describing neighboring genes Neighboring gene EFR3 homolog B Neighboring gene proopiomelanocortin Neighboring gene dystrobrevin beta Neighboring gene ASXL transcriptional regulator 2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA (cytosine-5-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
DNA (cytosine-5)-methyltransferase 3A
Names
DNA methyltransferase 3A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613640.1 Reference CriGri_1.0 Primary Assembly

    Range
    774575..893391 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016964036.3XP_016819525.1  DNA (cytosine-5)-methyltransferase 3A isoform X1

    UniProtKB/TrEMBL
    A0A8C2MN27, A0A9J7H6T7
    Conserved Domains (4) summary
    cd05835
    Location:286372
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PTZ00449
    Location:1124
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11729
    Location:483610
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:628791
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
  2. XM_035438558.1XP_035294449.1  DNA (cytosine-5)-methyltransferase 3A isoform X1

    UniProtKB/TrEMBL
    A0A8C2MN27, A0A9J7H6T7
    Conserved Domains (4) summary
    cd05835
    Location:286372
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PTZ00449
    Location:1124
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11729
    Location:483610
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:628791
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
  3. XM_035438560.1XP_035294451.1  DNA (cytosine-5)-methyltransferase 3A isoform X2

    UniProtKB/TrEMBL
    A0A9J7KC16
    Conserved Domains (3) summary
    cd05835
    Location:106192
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cd11729
    Location:303430
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:448611
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...

RNA

  1. XR_004767927.1 RNA Sequence

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048600.1 Alternate CriGri-PICRH-1.0

    Range
    14683412..14802579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027424549.2XP_027280350.1  DNA (cytosine-5)-methyltransferase 3A isoform X1

    UniProtKB/TrEMBL
    A0A8C2MN27, A0A9J7H6T7
    Conserved Domains (4) summary
    cd05835
    Location:286372
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PTZ00449
    Location:1124
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11729
    Location:483610
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:628791
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
  2. XM_035448203.1XP_035304094.1  DNA (cytosine-5)-methyltransferase 3A isoform X1

    UniProtKB/TrEMBL
    A0A8C2MN27, A0A9J7H6T7
    Related
    ENSCGRP00015035665.2, ENSCGRT00015043493.2
    Conserved Domains (4) summary
    cd05835
    Location:286372
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PTZ00449
    Location:1124
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11729
    Location:483610
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:628791
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
  3. XM_027424548.2XP_027280349.1  DNA (cytosine-5)-methyltransferase 3A isoform X1

    UniProtKB/TrEMBL
    A0A8C2MN27, A0A9J7H6T7
    Conserved Domains (4) summary
    cd05835
    Location:286372
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PTZ00449
    Location:1124
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11729
    Location:483610
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:628791
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
  4. XM_035448205.1XP_035304096.1  DNA (cytosine-5)-methyltransferase 3A isoform X2

    UniProtKB/TrEMBL
    A0A9J7KC16
    Conserved Domains (3) summary
    cd05835
    Location:106192
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cd11729
    Location:303430
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
    cl30459
    Location:448611
    Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...

RNA

  1. XR_003486954.2 RNA Sequence