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Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100771181, updated on 8-Mar-2024

Summary

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Gene symbol
Pik3r2
Gene description
phosphoinositide-3-kinase regulatory subunit 2
Locus tag
I79_005111
See related
Ensembl:ENSCGRG00015001303
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613716.1 (1051223..1058545, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (248233211..248241725)

NW_003613716.1Genomic Context describing neighboring genes Neighboring gene MPV17 mitochondrial inner membrane protein like 2 Neighboring gene IFI30 lysosomal thiol reductase Neighboring gene microtubule associated serine/threonine kinase 3 Neighboring gene interleukin 12 receptor subunit beta 1 Neighboring gene arrestin domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit beta
Names
Phosphatidylinositol 3-kinase regulatory subunit beta
phosphoinositide-3-kinase, regulatory subunit 2 (beta)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613716.1 Reference CriGri_1.0 Primary Assembly

    Range
    1051223..1058545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035451251.1 → XP_035307142.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A061IJT4, A0A9J7F6F3
    Conserved Domains (5) summary
    cd09930
    Location:609 → 712
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:316 → 426
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11909
    Location:7 → 80
    SH3_PI3K_p85beta; Src Homology 3 domain of the p85beta regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12926
    Location:431 → 591
    iSH2_PIK3R2; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 2, PIK3R2, also called p85beta
    cl02570
    Location:110 → 289
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    248233211..248241725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027394738.2 → XP_027250539.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A061IJT4, A0A9J7F6F3
    Related
    ENSCGRP00015001613.2, ENSCGRT00015002025.2
    Conserved Domains (5) summary
    cd09930
    Location:609 → 712
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:316 → 426
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11909
    Location:7 → 80
    SH3_PI3K_p85beta; Src Homology 3 domain of the p85beta regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12926
    Location:431 → 591
    iSH2_PIK3R2; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 2, PIK3R2, also called p85beta
    cl02570
    Location:110 → 289
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_027394739.2 → XP_027250540.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A061IJT4, A0A9J7F9A5
    Related
    ENSCGRP00015001560.2, ENSCGRT00015001962.2

  3. XM_027394741.2 → XP_027250542.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X5

    UniProtKB/TrEMBL
    A0A9J7J8V0

  4. XM_027394743.2 → XP_027250544.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X5

    UniProtKB/TrEMBL
    A0A9J7J8V0

  5. XM_027394740.2 → XP_027250541.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X4

    UniProtKB/TrEMBL
    A0A061IJT4, A0A9J7F425
Nucleotide Protein Strain
Heading Accession and Version

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