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Alox5 arachidonate 5-lipoxygenase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100772492, updated on 8-Mar-2024

Summary

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Gene symbol
Alox5
Gene description
arachidonate 5-lipoxygenase
See related
Ensembl:ENSCGRG00015005463
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
14
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003615722.1 (51179..96524, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 8 NC_048601.1 (28398309..28443842)

NW_003615722.1Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene uncharacterized LOC118237856 Neighboring gene olfactory receptor 13A1 Neighboring gene olfactory receptor 13A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 5-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polyunsaturated fatty acid 5-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003615722.1 Reference CriGri_1.0 Primary Assembly

    Range
    51179..96524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035437142.1 → XP_035293033.1  polyunsaturated fatty acid 5-lipoxygenase isoform X3

    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:224 → 633
    Lipoxygenase

  2. XM_035437141.1 → XP_035293032.1  polyunsaturated fatty acid 5-lipoxygenase isoform X2

    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:224 → 636
    Lipoxygenase

  3. XM_035437143.1 → XP_035293034.1  polyunsaturated fatty acid 5-lipoxygenase isoform X4

    UniProtKB/TrEMBL
    A0A8C2LS79
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:221 → 608
    Lipoxygenase

  4. XM_003513084.5 → XP_003513132.1  polyunsaturated fatty acid 5-lipoxygenase isoform X1

    See identical proteins and their annotated locations for XP_003513132.1

    UniProtKB/TrEMBL
    G3IE71
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:165 → 665
    Lipoxygenase; Lipoxygenase

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048601.1 Alternate CriGri-PICRH-1.0

    Range
    28398309..28443842
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027429216.2 → XP_027285017.1  polyunsaturated fatty acid 5-lipoxygenase isoform X1

    UniProtKB/TrEMBL
    A0A9J7GGJ1
    Related
    ENSCGRP00015007130.1, ENSCGRT00015008756.2

  2. XM_035448983.1 → XP_035304874.1  polyunsaturated fatty acid 5-lipoxygenase isoform X4

    UniProtKB/TrEMBL
    A0A9J7KCK5
    Related
    ENSCGRP00015007139.1, ENSCGRT00015008767.2
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:221 → 608
    Lipoxygenase

  3. XM_035448981.1 → XP_035304872.1  polyunsaturated fatty acid 5-lipoxygenase isoform X2

    UniProtKB/TrEMBL
    A0A9J7H6M6
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:221 → 636
    Lipoxygenase

  4. XM_035448982.1 → XP_035304873.1  polyunsaturated fatty acid 5-lipoxygenase isoform X3

    UniProtKB/TrEMBL
    A0A9J7K1E5
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:221 → 633
    Lipoxygenase
Nucleotide Protein Strain
Heading Accession and Version

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