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ERVK-18 endogenous retrovirus group K member 18 [ Homo sapiens (human) ]

Gene ID: 100775105, updated on 7-Mar-2021

Summary

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Official Symbol
ERVK-18provided by HGNC
Official Full Name
endogenous retrovirus group K member 18provided by HGNC
Primary source
HGNC:HGNC:39025
Gene type
other
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PR; env; c1_C; HERV-K18; Protease; Proteinase
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Genomic context

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Location:
1q23.3

Bibliography

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Related articles in PubMed

  1. Expression of human endogenous retrovirus HERV-K18 is associated with clinical severity in osteoarthritis patients. Garcia-Montojo M, et al. Scand J Rheumatol, 2013. PMID 23662747
  2. Role of the human endogenous retrovirus HERV-K18 in autoimmune disease susceptibility: study in the Spanish population and meta-analysis. de la Hera B, et al. PLoS One, 2013. PMID 23634223, Free PMC Article
  3. Association of human endogenous retrovirus K-18 polymorphisms with type 1 diabetes. Marguerat S, et al. Diabetes, 2004 Mar. PMID 14988274
  4. Autoantibodies to human endogenous retrovirus-K are frequently detected in health and disease and react with multiple epitopes. Herve CA, et al. Clin Exp Immunol, 2002 Apr. PMID 11982593, Free PMC Article
  5. Human endogenous retrovirus IDDMK(1,2)22 and mouse mammary tumor virus superantigens differ in their ability to stimulate murine T cell hybridomas. Azar GA, et al. Immunol Lett, 2002 Apr 1. PMID 11841850

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Formation of HERV-K and HERV-Fc1 Envelope Family Members is Suppressed on Transcriptional and Translational Level.
    Title: Formation of HERV-K and HERV-Fc1 Envelope Family Members is Suppressed on Transcriptional and Translational Level.
  2. downregulation of expression in the skin from Lichen planus patients
    Title: Human endogenous retrovirus expression is inversely related with the up-regulation of interferon-inducible genes in the skin of patients with lichen planus.
  3. Expression of human endogenous retrovirus HERV-K18 is associated with clinical severity in osteoarthritis patients.
    Title: Expression of human endogenous retrovirus HERV-K18 is associated with clinical severity in osteoarthritis patients.
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General gene information

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Other Names

  • Endogenous retrovirus group K member 18 Pro protein
  • Envelope polyprotein
  • HERV-K(C1a) Pro protein
  • HERV-K110 Pro protein
  • HERV-K18 Pro protein
  • HERV-K_1q23.3 provirus ancestral Env polyprotein
  • HERV-K_1q23.3 provirus ancestral Pol protein
  • HERV-K_1q23.3 provirus ancestral Pro protein
  • IDDMK1,2 22 envelope protein
  • IDDMK1,2 22 superantigen
  • IDDMK1,2-22
  • endogenous retrovirus K-18
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O42043.2 GenPept UniProtKB/Swiss-Prot:O42043
P63123.1 GenPept UniProtKB/Swiss-Prot:P63123

Gene LinkOut

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