mt-nd2 NADH dehydrogenase 2, mitochondrial [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mt-nd2provided by ZNC
Official Full Name: NADH dehydrogenase 2, mitochondrialprovided by ZNC
Primary source: ZFIN:ZDB-GENE-011205-8
See related: AllianceGenome:ZFIN:ZDB-GENE-011205-8
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as: mtnd2; ND2
Summary: Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Is expressed in several structures, including digestive system; immature eye; midbrain; musculature system; and segmental plate. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	MT (non-nuclear)	NC_002333.2 (4993..6039)
105	previous assembly	GRCz10 (GCF_000002035.5)	MT (non-nuclear)	NC_002333.2 (4993..6039)

Chromosome MT - NC_002333.2 Genomic Context describing neighboring genes

Genomic Sequence:

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Function	Evidence Code	Pubs
enables NADH dehydrogenase (ubiquinone) activity	IBA Inferred from Biological aspect of Ancestor more info
enables NADH dehydrogenase (ubiquinone) activity	IEA Inferred from Electronic Annotation more info
enables NADH dehydrogenase (ubiquinone) activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrial electron transport, NADH to ubiquinone	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial electron transport, NADH to ubiquinone	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of mitochondrial respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in respirasome	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain