rps-14 Small ribosomal subunit protein uS11 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: rps-14
Gene description: Small ribosomal subunit protein uS11
Primary source: WormBase:WBGene00004483
Locus tag: CELE_F37C12.9
See related: AllianceGenome:WB:WBGene00004483
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable mRNA 5'-UTR binding activity and small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal small subunit assembly; and translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in hypodermis; intestine; pharynx; and tail. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See rps-14 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (7178991..7179588, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ribosomal protein RPS-14 is able to modulate let-7 function in C. elegans
Title: Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F37C12.4 (e-PCR)
- UniSTS:320722

F37C12.9 (e-PCR)
- UniSTS:320723

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ribosomal small subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal small subunit biogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytosolic small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: Small ribosomal subunit protein uS11

NP_498572.1

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7178991..7179588 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066171.10 → NP_498572.1 Small ribosomal subunit protein uS11 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498572.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P48150

Conserved Domains (1) summary

PTZ00129
Location:2 → 141

PTZ00129; 40S ribosomal protein S14; Provisional