actl6a actin-like 6A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: actl6aprovided by ZNC
Official Full Name: actin-like 6Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-020419-36
See related: Ensembl:ENSDARG00000070828 AllianceGenome:ZFIN:ZDB-GENE-020419-36
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: baf53a; fb52e06; fl26e12; chunp6900; wu:fb52e06; wu:fl26e12
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in histone H4 acetylation; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to be part of NuA4 histone acetyltransferase complex and SWI/SNF complex. Is expressed in ventricular zone. Orthologous to human ACTL6A (actin like 6A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (29386734..29395707)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (29396168..29405144)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Mitotic exit in neurons is accompanied by an essential switch in ATP-dependent chromatin regulatory complexes from the neural progenitor Brg/Brm-associated factor (npBAF) to neuron-specific nBAF
Title: Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fb52e06.x1 (e-PCR)
- UniSTS:203289

fa97g10.y1 (e-PCR)
- UniSTS:189749

fj09g03.y1 (e-PCR)
- UniSTS:198495

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in nervous system development	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of NuA4 histone acetyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SWI/SNF complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: actin-like protein 6A

Names: BRG1/brm-associated factor 53A; etID38198.6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173240.1 → NP_775347.1 actin-like protein 6A

See identical proteins and their annotated locations for NP_775347.1

Status: PROVISIONAL

Source sequence(s)

AY099520

UniProtKB/TrEMBL

Q8JGS6

Related

ENSDARP00000095078.3, ENSDART00000104303.5

Conserved Domains (2) summary

pfam00022
Location:11 → 429

Actin; Actin

cl17037
Location:10 → 428

NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

29386734..29395707

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005165917.4 → XP_005165974.1 actin-like protein 6A isoform X1

UniProtKB/TrEMBL

A0A8M2BD91

Conserved Domains (2) summary

pfam00022
Location:11 → 455

Actin; Actin

cl17037
Location:10 → 454

NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily