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Rps24 ribosomal protein S24 [ Mus musculus (house mouse) ]

Gene ID: 20088, updated on 3-Apr-2024

Summary

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Official Symbol
Rps24provided by MGI
Official Full Name
ribosomal protein S24provided by MGI
Primary source
MGI:MGI:98147
See related
Ensembl:ENSMUSG00000025290 AllianceGenome:MGI:98147
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable translation initiation factor binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in erythrocyte homeostasis; rRNA processing; and ribosomal small subunit biogenesis. Predicted to act upstream of or within translation. Predicted to be located in cytosolic ribosome and endoplasmic reticulum. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-blackfan anemia 3. Orthologous to human RPS24 (ribosomal protein S24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 223.6), bladder adult (RPKM 143.0) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Rps24 in Genome Data Viewer
Location:
14 A3; 14 14.42 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (24540786..24545925)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (24490678..24496960)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 47814 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide A Neighboring gene STARR-seq mESC enhancer starr_36195 Neighboring gene predicted gene, 31720 Neighboring gene STARR-seq mESC enhancer starr_36198 Neighboring gene predicted gene, 31775 Neighboring gene STARR-seq mESC enhancer starr_36199 Neighboring gene STARR-seq mESC enhancer starr_36200 Neighboring gene STARR-seq mESC enhancer starr_36202 Neighboring gene predicted gene, 31951

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Nucleotide sequences of a cDNA clone encoding mouse ribosomal protein S24. Ro HS, et al. Nucleic Acids Res, 1991 Dec 11. PMID 1840675, Free PMC Article
  2. Development of Soft Tissue Sarcomas in Ribosomal Proteins L5 and S24 Heterozygous Mice. Kazerounian S, et al. J Cancer, 2016. PMID 26722357, Free PMC Article
  3. Molecular characterization of the mouse ribosomal protein S24 multigene family: a uniquely expressed intron-containing gene with cell-specific expression of three alternatively spliced mRNAs. Xu L, et al. Nucleic Acids Res, 1994 Feb 25. PMID 8127713, Free PMC Article
  4. Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. De Arras L, et al. Genetics, 2014 Jun. PMID 24361939, Free PMC Article
  5. The S29 ribosomal protein increases tumor suppressor activity of K rev-1 gene on v-K ras-transformed NIH3T3 cells. Kondoh N, et al. Biochim Biophys Acta, 1996 Aug 21. PMID 8781548

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC107549

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables translation initiation factor binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in erythrocyte homeostasis ISO
Inferred from Sequence Orthology
more info
  
involved_in rRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 PubMed 
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
part_of small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
small ribosomal subunit protein eS24
Names
40S ribosomal protein S24
MRP S24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360584.2 → NP_001347513.1  small ribosomal subunit protein eS24 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC154573
    UniProtKB/TrEMBL
    Q9D7P1, Q9DCA4
    Conserved Domains (1) summary
    PTZ00071
    Location:1 → 130
    PTZ00071; 40S ribosomal protein S24; Provisional

  2. NM_001360585.2 → NP_001347514.1  small ribosomal subunit protein eS24 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154573
    UniProtKB/TrEMBL
    Q9DCA4
    Conserved Domains (1) summary
    PTZ00071
    Location:1 → 130
    PTZ00071; 40S ribosomal protein S24; Provisional

  3. NM_001360586.2 → NP_001347515.1  small ribosomal subunit protein eS24 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC154573
    Consensus CDS
    CCDS88598.1
    UniProtKB/TrEMBL
    A0A286YEB7, Q9DCA4
    Related
    ENSMUSP00000153637.2, ENSMUST00000224568.2
    Conserved Domains (1) summary
    cl00878
    Location:1 → 118
    Ribosomal_S24e; Ribosomal protein S24e

  4. NM_001424557.1 → NP_001411486.1  small ribosomal subunit protein eS24 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC154573
    UniProtKB/TrEMBL
    Q9CQK2

  5. NM_001424558.1 → NP_001411487.1  small ribosomal subunit protein eS24 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154573

  6. NM_001424559.1 → NP_001411488.1  small ribosomal subunit protein eS24 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154573

  7. NM_001424560.1 → NP_001411489.1  small ribosomal subunit protein eS24 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154573

  8. NM_001424561.1 → NP_001411490.1  small ribosomal subunit protein eS24 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154573

  9. NM_001424562.1 → NP_001411491.1  small ribosomal subunit protein eS24 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC154573

  10. NM_001424563.1 → NP_001411492.1  small ribosomal subunit protein eS24 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC154573

  11. NM_001424564.1 → NP_001411493.1  small ribosomal subunit protein eS24 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC154573

  12. NM_001424565.1 → NP_001411494.1  small ribosomal subunit protein eS24 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC154573
    UniProtKB/TrEMBL
    A0A286YEB7

  13. NM_001424566.1 → NP_001411495.1  small ribosomal subunit protein eS24 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC154573
    UniProtKB/TrEMBL
    A0A286YEB7

  14. NM_001424567.1 → NP_001411496.1  small ribosomal subunit protein eS24 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC154573

  15. NM_001424568.1 → NP_001411497.1  small ribosomal subunit protein eS24 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC154573

  16. NM_001424569.1 → NP_001411498.1  small ribosomal subunit protein eS24 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC154573

  17. NM_001424570.1 → NP_001411499.1  small ribosomal subunit protein eS24 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC154573

  18. NM_001424571.1 → NP_001411500.1  small ribosomal subunit protein eS24 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC154573

  19. NM_011297.4 → NP_035427.2  small ribosomal subunit protein eS24 isoform 1

    See identical proteins and their annotated locations for NP_035427.2

    Status: VALIDATED

    Source sequence(s)
    AC154573
    Consensus CDS
    CCDS36830.1
    UniProtKB/TrEMBL
    Q9DCA4
    Related
    ENSMUSP00000125977.3, ENSMUST00000169826.3
    Conserved Domains (1) summary
    PTZ00071
    Location:1 → 130
    PTZ00071; 40S ribosomal protein S24; Provisional

  20. NM_207634.3 → NP_997517.1  small ribosomal subunit protein eS24 isoform 2

    See identical proteins and their annotated locations for NP_997517.1

    Status: VALIDATED

    Source sequence(s)
    AC154573
    Consensus CDS
    CCDS36829.1
    UniProtKB/Swiss-Prot
    P62849, Q642L0, Q6PDB5
    UniProtKB/TrEMBL
    Q3TIF8, Q5M9M7, Q9CY61
    Related
    ENSMUSP00000152944.2, ENSMUST00000225023.2
    Conserved Domains (1) summary
    PTZ00071
    Location:1 → 130
    PTZ00071; 40S ribosomal protein S24; Provisional

  21. NM_207635.3 → NP_997518.1  small ribosomal subunit protein eS24 isoform 3

    See identical proteins and their annotated locations for NP_997518.1

    Status: VALIDATED

    Source sequence(s)
    AC154573
    Consensus CDS
    CCDS88597.1
    UniProtKB/TrEMBL
    Q9DCA4
    Related
    ENSMUSP00000153659.2, ENSMUST00000223999.2
    Conserved Domains (1) summary
    PTZ00071
    Location:1 → 130
    PTZ00071; 40S ribosomal protein S24; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    24540786..24545925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62849.1 GenPept UniProtKB/Swiss-Prot:P62849

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