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Rps4x ribosomal protein S4, X-linked [ Mus musculus (house mouse) ]

Gene ID: 20102, updated on 11-Apr-2024

Summary

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Official Symbol
Rps4xprovided by MGI
Official Full Name
ribosomal protein S4, X-linkedprovided by MGI
Primary source
MGI:MGI:98158
See related
Ensembl:ENSMUSG00000031320 AllianceGenome:MGI:98158
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rps4; Rps4-1
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Is active in synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to several human genes including RPS4X (ribosomal protein S4 X-linked). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 580.8), liver E14 (RPKM 549.2) and 23 other tissues See more
Orthologs
human all
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Genomic context

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Location:
X D; X 45.2 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (101228548..101232929, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (102184941..102189391, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene excision repair cross-complementing rodent repair deficiency complementation group 6 like Neighboring gene STARR-positive B cell enhancer ABC_E2538 Neighboring gene protein phosphatase 1 regulatory subunit 14B pseudogene Neighboring gene predicted gene 14859 Neighboring gene Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression level of Rps4 mRNA in 39,X mice and 40,XX mice. Omoe K, et al. Cytogenet Cell Genet, 1994. PMID 8187552
  2. Inactivation of the Rps4 gene on the mouse X chromosome. Zinn AR, et al. Genomics, 1991 Dec. PMID 1783379
  3. Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system. Bressler SL, et al. Somat Cell Mol Genet, 1993 Jan. PMID 7681608
  4. Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons. Shen SI, et al. Mol Genet Metab, 1998 Feb. PMID 9562962
  5. Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Fisher EM, et al. Cell, 1990 Dec 21. PMID 2124517

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC102174, MGC118104

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
  
located_in ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of small ribosomal subunit ISA
Inferred from Sequence Alignment
more info
 PubMed 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
small ribosomal subunit protein eS4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001425993.1 → NP_001412922.1  small ribosomal subunit protein eS4 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AL954850

  2. NM_001425994.1 → NP_001412923.1  small ribosomal subunit protein eS4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL954850

  3. NM_001425995.1 → NP_001412924.1  small ribosomal subunit protein eS4 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL954850
    UniProtKB/TrEMBL
    Q545F8

  4. NM_009094.3 → NP_033120.1  small ribosomal subunit protein eS4 isoform 2

    See identical proteins and their annotated locations for NP_033120.1

    Status: VALIDATED

    Source sequence(s)
    AL954850
    Consensus CDS
    CCDS41083.1
    UniProtKB/Swiss-Prot
    P62702, Q9CXN0
    UniProtKB/TrEMBL
    Q3UXQ6, Q545X8
    Related
    ENSMUSP00000033683.8, ENSMUST00000033683.8
    Conserved Domains (1) summary
    PLN00036
    Location:1 → 260
    PLN00036; 40S ribosomal protein S4; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    101228548..101232929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62702.2 GenPept UniProtKB/Swiss-Prot:P62702

Gene LinkOut

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