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SCMH1 Scm polycomb group protein homolog 1 [ Homo sapiens (human) ]

Gene ID: 22955, updated on 7-Apr-2024

Summary

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Official Symbol
SCMH1provided by HGNC
Official Full Name
Scm polycomb group protein homolog 1provided by HGNC
Primary source
HGNC:HGNC:19003
See related
Ensembl:ENSG00000010803 MIM:616396; AllianceGenome:HGNC:19003
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Scml3
Summary
Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within anterior/posterior pattern specification; chromatin remodeling; and spermatogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 14.6), ovary (RPKM 12.4) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
1p34.2
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (41027202..41242306, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (40896567..41111749, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (41492874..41707978, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 739 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 740 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 858 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 859 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:41472557-41473756 Neighboring gene CTP synthase 1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_8011 Neighboring gene SLFNL1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:41492537-41493455 Neighboring gene MPRA-validated peak193 silencer Neighboring gene schlafen like 1 Neighboring gene ribosomal protein L23a pseudogene 17 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:41622311-41622500 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 741 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 742 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 743 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:41715456-41715624 Neighboring gene SCMH1 divergent transcript Neighboring gene Sharpr-MPRA regulatory region 3563 Neighboring gene ribosomal protein L36a pseudogene 9 Neighboring gene uncharacterized LOC124904158

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34. Berger J, et al. Gene, 1999 Sep 3. PMID 10524249
  2. A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro. Tomotsune D, et al. Differentiation, 1999 Dec. PMID 10653359
  3. Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. Ohtsubo M, et al. Proc Natl Acad Sci U S A, 2008 Jul 29. PMID 18650381, Free PMC Article
  4. Genome-wide association analysis identifies 20 loci that influence adult height. Weedon MN, et al. Nat Genet, 2008 May. PMID 18391952, Free PMC Article
  5. The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions. Luo L, et al. Nature, 2004 Feb 19. PMID 14973489

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Observational study of gene-disease association. (HuGE Navigator)
    Title: The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association analysis identifies 20 loci that influence adult height.
EBI GWAS Catalog
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
EBI GWAS Catalog
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in heterochromatin formation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
polycomb protein SCMH1
Names
sex comb on midleg homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031694.3 → NP_001026864.1  polycomb protein SCMH1 isoform a

    See identical proteins and their annotated locations for NP_001026864.1

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS30688.1
    UniProtKB/Swiss-Prot
    B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
    UniProtKB/TrEMBL
    B3KMZ7
    Related
    ENSP00000318094.7, ENST00000326197.11
    Conserved Domains (5) summary
    cd09578
    Location:587 → 657
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:233 → 357
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:358 → 466
    SLED; SLED domain
    pfam17208
    Location:271 → 324
    RBR; RNA binding Region

  2. NM_001172218.2 → NP_001165689.1  polycomb protein SCMH1 isoform c

    See identical proteins and their annotated locations for NP_001165689.1

    Status: VALIDATED

    Source sequence(s)
    AF149046, AL606484, BC009752, BC021252
    Consensus CDS
    CCDS53301.1
    UniProtKB/TrEMBL
    B3KMZ7
    Related
    ENSP00000361677.1, ENST00000372596.5
    Conserved Domains (5) summary
    cd09578
    Location:504 → 574
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:76 → 174
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:172 → 296
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:297 → 405
    SLED; SLED domain
    pfam17208
    Location:210 → 263
    RBR; RNA binding Region

  3. NM_001172219.2 → NP_001165690.1  polycomb protein SCMH1 isoform d

    Status: VALIDATED

    Source sequence(s)
    AK023124, AL606484, BC021252
    Consensus CDS
    CCDS53304.1
    UniProtKB/TrEMBL
    B3KMZ7
    Related
    ENSP00000337352.5, ENST00000337495.9
    Conserved Domains (3) summary
    cd09578
    Location:575 → 645
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:41 → 136
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03307
    Location:183 → 369
    PHA03307; transcriptional regulator ICP4; Provisional

  4. NM_001172220.2 → NP_001165691.1  polycomb protein SCMH1 isoform c

    See identical proteins and their annotated locations for NP_001165691.1

    Status: VALIDATED

    Source sequence(s)
    AL606484, BC021252, BX640721
    Consensus CDS
    CCDS53301.1
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:504 → 574
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:76 → 174
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:172 → 296
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:297 → 405
    SLED; SLED domain
    pfam17208
    Location:210 → 263
    RBR; RNA binding Region

  5. NM_001172221.3 → NP_001165692.1  polycomb protein SCMH1 isoform e

    See identical proteins and their annotated locations for NP_001165692.1

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS53302.1
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:526 → 596
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:76 → 174
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:172 → 296
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:297 → 405
    SLED; SLED domain
    pfam17208
    Location:210 → 263
    RBR; RNA binding Region

  6. NM_001172222.3 → NP_001165693.1  polycomb protein SCMH1 isoform f

    See identical proteins and their annotated locations for NP_001165693.1

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS53303.1
    UniProtKB/Swiss-Prot
    Q96GD3
    Related
    ENSP00000403974.2, ENST00000456518.3
    Conserved Domains (4) summary
    cd09578
    Location:407 → 477
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00454
    Location:410 → 477
    SAM; Sterile alpha motif
    smart00561
    Location:2 → 79
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam12140
    Location:200 → 308
    DUF3588; Protein of unknown function (DUF3588)

  7. NM_001350667.2 → NP_001337596.1  polycomb protein SCMH1 isoform g

    Status: VALIDATED

    Source sequence(s)
    AF149046, AL110502, AL606484, BC009752, BC021252, BG024566
    Conserved Domains (5) summary
    cd09578
    Location:496 → 566
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:46 → 144
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:142 → 266
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:267 → 375
    SLED; SLED domain
    pfam17208
    Location:180 → 233
    RBR; RNA binding Region

  8. NM_001350668.2 → NP_001337597.1  polycomb protein SCMH1 isoform h

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Conserved Domains (5) summary
    cd09578
    Location:397 → 467
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    pfam02820
    Location:4 → 67
    MBT; mbt repeat
    pfam12140
    Location:190 → 298
    SLED; SLED domain
    pfam17208
    Location:103 → 156
    RBR; RNA binding Region
    cl26464
    Location:65 → 189
    Atrophin-1; Atrophin-1 family

  9. NM_001394299.1 → NP_001381228.1  polycomb protein SCMH1 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (3) summary
    cd09578
    Location:565 → 635
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03307
    Location:173 → 359
    PHA03307; transcriptional regulator ICP4; Provisional

  10. NM_001394300.1 → NP_001381229.1  polycomb protein SCMH1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS30688.1
    UniProtKB/Swiss-Prot
    B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:587 → 657
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:233 → 357
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:358 → 466
    SLED; SLED domain
    pfam17208
    Location:271 → 324
    RBR; RNA binding Region

  11. NM_001394301.1 → NP_001381230.1  polycomb protein SCMH1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS30688.1
    UniProtKB/Swiss-Prot
    B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:587 → 657
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:233 → 357
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:358 → 466
    SLED; SLED domain
    pfam17208
    Location:271 → 324
    RBR; RNA binding Region

  12. NM_001394302.1 → NP_001381231.1  polycomb protein SCMH1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS30688.1
    UniProtKB/Swiss-Prot
    B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:587 → 657
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:233 → 357
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:358 → 466
    SLED; SLED domain
    pfam17208
    Location:271 → 324
    RBR; RNA binding Region

  13. NM_001394303.1 → NP_001381232.1  polycomb protein SCMH1 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS53302.1
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:526 → 596
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:76 → 174
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:172 → 296
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:297 → 405
    SLED; SLED domain
    pfam17208
    Location:210 → 263
    RBR; RNA binding Region

  14. NM_001394304.1 → NP_001381233.1  polycomb protein SCMH1 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (3) summary
    cd09578
    Location:565 → 635
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03307
    Location:173 → 359
    PHA03307; transcriptional regulator ICP4; Provisional

  15. NM_001394305.1 → NP_001381234.1  polycomb protein SCMH1 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (3) summary
    cd09578
    Location:565 → 635
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03307
    Location:173 → 359
    PHA03307; transcriptional regulator ICP4; Provisional

  16. NM_001394306.1 → NP_001381235.1  polycomb protein SCMH1 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (3) summary
    cd09578
    Location:565 → 635
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:31 → 126
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03307
    Location:173 → 359
    PHA03307; transcriptional regulator ICP4; Provisional

  17. NM_001394307.1 → NP_001381236.1  polycomb protein SCMH1 isoform j

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (5) summary
    cd09578
    Location:540 → 610
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:90 → 188
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:186 → 310
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:311 → 419
    SLED; SLED domain
    pfam17208
    Location:224 → 277
    RBR; RNA binding Region

  18. NM_001394308.1 → NP_001381237.1  polycomb protein SCMH1 isoform k

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS90927.1
    UniProtKB/TrEMBL
    A0A8Q3SHR9, B3KMZ7
    Related
    ENSP00000511814.1, ENST00000695336.1
    Conserved Domains (3) summary
    cd09578
    Location:477 → 547
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:41 → 136
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam12140
    Location:248 → 356
    SLED; SLED domain

  19. NM_001394309.1 → NP_001381238.1  polycomb protein SCMH1 isoform l

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Conserved Domains (5) summary
    cd09578
    Location:419 → 489
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    PHA03247
    Location:65 → 189
    PHA03247; large tegument protein UL36; Provisional
    pfam02820
    Location:4 → 67
    MBT; mbt repeat
    pfam12140
    Location:190 → 298
    SLED; SLED domain
    pfam17208
    Location:103 → 156
    RBR; RNA binding Region

  20. NM_001394311.1 → NP_001381240.1  polycomb protein SCMH1 isoform m

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484
    Consensus CDS
    CCDS90928.1
    UniProtKB/TrEMBL
    A0A8Q3SHN2, B3KMZ7
    Related
    ENSP00000511813.1, ENST00000695335.1
    Conserved Domains (5) summary
    cd09578
    Location:597 → 667
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:41 → 136
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:243 → 367
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:368 → 476
    SLED; SLED domain
    pfam17208
    Location:281 → 334
    RBR; RNA binding Region

  21. NM_012236.4 → NP_036368.1  polycomb protein SCMH1 isoform b

    See identical proteins and their annotated locations for NP_036368.1

    Status: VALIDATED

    Source sequence(s)
    AF149045, AL606484, BC009752, BC021252
    Consensus CDS
    CCDS461.1
    UniProtKB/TrEMBL
    B3KMZ7
    Related
    ENSP00000361678.1, ENST00000372597.5
    Conserved Domains (5) summary
    cd09578
    Location:518 → 588
    SAM_Scm; SAM domain of Scm proteins of Polycomb group
    smart00561
    Location:90 → 188
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    PHA03247
    Location:186 → 310
    PHA03247; large tegument protein UL36; Provisional
    pfam12140
    Location:311 → 419
    SLED; SLED domain
    pfam17208
    Location:224 → 277
    RBR; RNA binding Region

RNA

  1. NR_135092.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL110502, AL391730, AL606484

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    41027202..41242306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047449591.1 → XP_047305547.1  polycomb protein SCMH1 isoform X10

  2. XM_011541034.2 → XP_011539336.1  polycomb protein SCMH1 isoform X4

    UniProtKB/TrEMBL
    B3KMZ7
    Conserved Domains (2) summary
    smart00561
    Location:41 → 136
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam12140
    Location:368 → 476
    DUF3588; Protein of unknown function (DUF3588)

  3. XM_047449589.1 → XP_047305545.1  polycomb protein SCMH1 isoform X9

    UniProtKB/TrEMBL
    A0A8Q3SHR9

  4. XM_047449568.1 → XP_047305524.1  polycomb protein SCMH1 isoform X3

  5. XM_047449564.1 → XP_047305520.1  polycomb protein SCMH1 isoform X1

    UniProtKB/TrEMBL
    A0A8Q3SHN2

  6. XM_047449565.1 → XP_047305521.1  polycomb protein SCMH1 isoform X1

    UniProtKB/TrEMBL
    A0A8Q3SHN2

  7. XM_047449567.1 → XP_047305523.1  polycomb protein SCMH1 isoform X2

    UniProtKB/Swiss-Prot
    B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6

  8. XM_047449577.1 → XP_047305533.1  polycomb protein SCMH1 isoform X5

  9. XM_047449578.1 → XP_047305534.1  polycomb protein SCMH1 isoform X6

    Related
    ENSP00000361676.1, ENST00000372595.5

  10. XM_047449583.1 → XP_047305539.1  polycomb protein SCMH1 isoform X6

  11. XM_047449587.1 → XP_047305543.1  polycomb protein SCMH1 isoform X7

  12. XM_047449588.1 → XP_047305544.1  polycomb protein SCMH1 isoform X8

    UniProtKB/TrEMBL
    B4DWE6
    Related
    ENSP00000511815.1, ENST00000695337.1

  13. XM_047449601.1 → XP_047305557.1  polycomb protein SCMH1 isoform X12

  14. XM_011541040.3 → XP_011539342.1  polycomb protein SCMH1 isoform X11

    Conserved Domains (2) summary
    smart00561
    Location:41 → 136
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam12140
    Location:368 → 476
    DUF3588; Protein of unknown function (DUF3588)

RNA

  1. XR_946584.3 RNA Sequence

  2. XR_007096354.1 RNA Sequence

  3. XR_002959761.2 RNA Sequence

  4. XR_007096355.1 RNA Sequence

  5. XR_007096359.1 RNA Sequence

  6. XR_007096358.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    40896567..41111749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054335231.1 → XP_054191206.1  polycomb protein SCMH1 isoform X10

  2. XM_054335223.1 → XP_054191198.1  polycomb protein SCMH1 isoform X4

  3. XM_054335230.1 → XP_054191205.1  polycomb protein SCMH1 isoform X9

    UniProtKB/TrEMBL
    A0A8Q3SHR9

  4. XM_054335222.1 → XP_054191197.1  polycomb protein SCMH1 isoform X3

  5. XM_054335219.1 → XP_054191194.1  polycomb protein SCMH1 isoform X1

    UniProtKB/TrEMBL
    A0A8Q3SHN2

  6. XM_054335220.1 → XP_054191195.1  polycomb protein SCMH1 isoform X1

    UniProtKB/TrEMBL
    A0A8Q3SHN2

  7. XM_054335221.1 → XP_054191196.1  polycomb protein SCMH1 isoform X2

    UniProtKB/Swiss-Prot
    B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6

  8. XM_054335224.1 → XP_054191199.1  polycomb protein SCMH1 isoform X5

  9. XM_054335225.1 → XP_054191200.1  polycomb protein SCMH1 isoform X6

  10. XM_054335226.1 → XP_054191201.1  polycomb protein SCMH1 isoform X6

  11. XM_054335227.1 → XP_054191202.1  polycomb protein SCMH1 isoform X13

  12. XM_054335228.1 → XP_054191203.1  polycomb protein SCMH1 isoform X7

  13. XM_054335229.1 → XP_054191204.1  polycomb protein SCMH1 isoform X8

    UniProtKB/TrEMBL
    B4DWE6

  14. XM_054335236.1 → XP_054191211.1  polycomb protein SCMH1 isoform X12

  15. XM_054335232.1 → XP_054191207.1  polycomb protein SCMH1 isoform X11

  16. XM_054335233.1 → XP_054191208.1  polycomb protein SCMH1 isoform X14

  17. XM_054335235.1 → XP_054191210.1  polycomb protein SCMH1 isoform X16

  18. XM_054335234.1 → XP_054191209.1  polycomb protein SCMH1 isoform X15

RNA

  1. XR_008485963.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96GD3.1 GenPept UniProtKB/Swiss-Prot:Q96GD3

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