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PF3D7_0716600 cysteine desulfurase [ Plasmodium falciparum 3D7 ]

Gene ID: 2655112, updated on 31-Jan-2024

Summary

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Gene symbol
PF3D7_0716600
Gene description
cysteine desulfurase
Locus tag
PF3D7_0716600
Gene type
protein coding
RNA name
cysteine desulfurase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 7
Exon count:
2
Sequence:
Chromosome: 7; NC_004328.3 (725296..727219)

Chromosome 7 - NC_004328.3Genomic Context describing neighboring genes Neighboring gene transcription initiation factor IIA subunit 1, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene eukaryotic translation initiation factor 3 subunit I, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004328.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sulfur mobilization for Fe-S cluster assembly by the essential SUF pathway in the Plasmodium falciparum apicoplast and its inhibition. Charan M, et al. Antimicrob Agents Chemother, 2014 Jun. PMID 24709262, Free PMC Article
  2. The suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasites. Gisselberg JE, et al. PLoS Pathog, 2013. PMID 24086138, Free PMC Article
  3. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables cysteine desulfurase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cysteine metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in apicoplast HDA PubMed 
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
cysteine desulfurase
XP_001349069.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004328.3 Reference assembly

    Range
    725296..727219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001349033.1 → XP_001349069.1  cysteine desulfurase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001349069.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q8IBT4
    UniProtKB/TrEMBL
    A0A024VA81, A0A024WB95, A0A0L7KDL2, W7FHP0, W7G8L5, W7K8W4
    Conserved Domains (1) summary
    cl18945
    Location:65 → 530
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
Nucleotide Protein
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