U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG33303 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768916, updated on 29-Dec-2023

Summary

Go to the top of the page Help
Official Symbol
CG33303provided by FlyBase
Primary source
FLYBASE:FBgn0053303
Locus tag
Dmel_CG33303
See related
AllianceGenome:FB:FBgn0053303
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5364; Dmel\CG33303; OST
Summary
Predicted to be involved in protein N-linked glycosylation via asparagine. Located in endomembrane system. Is expressed in adult heart. Orthologous to human RPN1 (ribophorin I). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
31D11-31D11; 2-41 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10373369..10375757, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10373369..10375757, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lowfat Neighboring gene uncharacterized protein Neighboring gene rhomboid-5 Neighboring gene defective proboscis extension response 19 Neighboring gene garnysstan Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Altered protein glycosylation predicts Alzheimer's disease and modulates its pathology in disease model Drosophila. Frenkel-Pinter M, et al. Neurobiol Aging, 2017 Aug. PMID 28552182
  2. Drosophila mojavensis - chico. Congleton H, et al. MicroPubl Biol, 2022. PMID 36468157, Free PMC Article
  3. Insights from Drosophila melanogaster model of Alzheimer's disease. Tue NT, et al. Front Biosci (Landmark Ed), 2020 Jan 1. PMID 31585881
  4. 5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity. Bernstein AI, et al. Hum Mol Genet, 2016 Jun 15. PMID 27060332, Free PMC Article
  5. An evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer's disease. Sivanantharajah L, et al. J Neurosci Methods, 2019 May 1. PMID 30633936

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in protein N-linked glycosylation via asparagine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG33303-PA
CG33303-PB

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10373369..10375757 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273406.1 → NP_001260335.1  uncharacterized protein Dmel_CG33303, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260335.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q76NQ0, R9S0M5
    Conserved Domains (1) summary
    pfam04597
    Location:35 → 444
    Ribophorin_I; Ribophorin I

  2. NM_205958.3 → NP_995680.1  uncharacterized protein Dmel_CG33303, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995680.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q76NQ0, R9S0M5
    Conserved Domains (1) summary
    pfam04597
    Location:35 → 444
    Ribophorin_I; Ribophorin I
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q76NQ0 Q76NQ0
Q8IH64 Q8IH64

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous